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HHS SBIR PA-11-134

Lab to Marketplace: Tools for Brain and Behavioral Research

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Agency: Department of Health and Human Services
Program/Year: SBIR / 2011
Solicitation Number: PA-11-134
Release Date: February 25, 2011
Open Date: March 5, 2011
Close Date: January 8, 2014
PA-11-134: Lab to Marketplace: Tools for Brain and Behavioral Research

Research Objectives

The National Institutes of Health (NIH) Blueprint for Neuroscience Research is a collaborative effort among the NIH Office of the Director and 15 Institutes and Centers to accelerate the pace of discovery and understanding in neuroscience research ( This FOA is affiliated with the Neuroscience Blueprint, with Institutes and Centers participating independently, and with participation by Institutes that are not part of the Neuroscience Blueprint.

The NIH and other research sponsors invest a significant amount of funds in the development of new technologies to study the brain and behavior, from basic and clinical perspectives, through a variety of mechanisms, including, from NIH, the R01, R21, R33, P01, P41, and P50 grants. This investment has produced a large number of technologies that include hardware (e.g., instruments, devices, etc.), software (e.g., computational models, informatics tools, data analytic methods, etc.) and wetware (e.g., cell-free assays, bioactive agents, imaging probes, etc.). While these technologies are put to good use by their developers, such non-commercial developers devote little attention to making their tools robust and easy to use by the broad research community. Consequently, the promise of these advanced technologies is often realized only by the tools' developers and their close associates. Moreover, ongoing support to maintain and update technologies in non-commercial settings is difficult to obtain.

In contrast, tools that are commercially available need to be sturdy and easy to use, and commercial success often provides the means for continued maintenance and improvements of the underlying technology. This FOA is intended to help move useful technologies from non-commercial laboratories into the commercial marketplace by inviting SBIR grant applications from small businesses for further development of such technologies that are relevant to the missions of the sponsoring NIH institutes and centers. The supported research and development will likely include making the tools more robust and easy to use, and will likely require close collaboration between the original developers of these technologies and SBCs. These partnerships may be accomplished in any of a number of ways, including the use of multiple principle investigators.

This FOA invites SBIR grant applications to commercially develop tools of any type relevant to the mission of one or more of the participating NIH institutes and centers.