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LUCERNA INC
http://www.lucernatechnologies.com
UEI: J3MWGA6WFCG3
# of Employees: 7
HUBZone Owned: No
Socially and Economically Disadvantaged: No
Woman Owned: No
Award Charts
Award Listing
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Fluorescent reporters for real time single cell Pol III transcription measurement
Amount: $176,165.00SUMMARY RNA polymerase III Pol III is increasingly recognized as an important drug target and a rapidly developing area of academic research Pol III is responsible for generating RNAs that are crit ...
SBIRPhase I2017Department of Health and Human Services National Institutes of Health -
Splice sensors for cancer drug discovery
Amount: $224,251.00SUMMARY Targeting pyruvate kinase remains a challenge in cancer drug discovery Despite compelling evidence highlighting the importance of the pyruvate kinase isoform M PKM in cancer cell growth ...
SBIRPhase I2016Department of Health and Human Services National Institutes of Health -
Fluorescent RNA foci assay for FXTAS drug discovery
Amount: $207,922.00PROJECT SUMMARY Fragile X-associated tremor/ataxia syndrome (FXTAS) is a progressive neurodegenerative disorder that that predominately affects adults over the age of 50. Individuals afflicted with ...
SBIRPhase I2014Department of Health and Human Services National Institutes of Health -
New toolkit to visualize RNAs in living cells
Amount: $1,248,733.00DESCRIPTION provided by applicant Over the past years it has become increasingly apparent that there is exceptional complexity in the RNA population in cells This diverse RNA pool includes micr ...
SBIRPhase II2014Department of Health and Human Services National Institutes of Health -
Live-Cell Assays of ER and Golgi Enzyme Activities
Amount: $298,937.00DESCRIPTION: Sirtuins and ADP ribosyltransferases (ARDTs) are two families of related enzymes that have important medically relevant functions. For example, SIRT3, a mitochondrial sirtuin, controls m ...
SBIRPhase I2013Department of Health and Human Services National Institutes of Health -
SBIR Phase I: Live-cell metabolite sensors for improving biofuel production
Amount: $149,733.00This Small Business Innovation Research (SBIR) Phase I project involves the development of fluorescent metabolite sensors that enable high-throughput screening of genetically improved biofuel-producin ...
SBIRPhase I2013National Science Foundation -
Methyltransferease sensors for homogenous HTS assays
Amount: $216,247.00DESCRIPTION (provided by applicant): Methyltransferases (MTs) are a diverse class of enzymes that catalyze the transfer of a methyl group from S-adenosylmethionine (SAM) to a substrate molecule. MTs c ...
SBIRPhase I2012Department of Health and Human Services National Institutes of Health -
New toolkit to visualize RNAs in living cells
Amount: $315,412.00DESCRIPTION (provided by applicant): Over the past 10 years it has become increasingly apparent that there is exceptional complexity in the RNA population in cells, including microRNAs, Piwi-interacti ...
SBIRPhase I2012Department of Health and Human Services National Institutes of Health -
Clozapine Sensors for Improving Therapeutic Treatments of Schizophrenia
Amount: $328,597.00DESCRIPTION (provided by applicant): Schizophrenia is a chronic and debilitating brain disorder that affects about 1.1 percent of the US population age 18 and older in a given year and account for 5% ...
SBIRPhase I2011Department of Health and Human Services National Institutes of Health