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Displaying 1971 – 1980 of 3738 Topics
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: The teen birth rate in the US remains high, particularly among racial/ethnic minorities compared with many other industrialized nations. The adverse consequences of teen pregnancy are substantial at individual, family, and community levels. A range of innovative tools and interventions… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: Dengue is a major public health problem in global tropical and subtropical areas. Primary prevention of this mosquito vector-borne (transmitted) disease is limited because vaccines are only in the late-stage development phase and vector control has been thus far unsuccessful. Dengue… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: Arthropod-borne virus infections may present with clinical symptoms similar to those of other bacterial or viral infections, such as a flu-like illness, encephalitis, or polio-like myelitis. Laboratory diagnosis is essential to determine etiology and calculate disease burden in order to… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: The reduction and eventual elimination of healthcare-associated infections (HAIs) and the combatting of antibiotic resistance in the pathogens causing these infections are national public health priorities as demonstrated in Department of Health and Human Services (HHS) national action… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: Substantial progress has been made recently towards identifying effective HIV prevention strategies. The RV144 trial demonstrated that an HIV vaccine comprised of a recombinant ALVAC prime + gp120 boost regimen was partially efficacious (VE=31.2%), although it’s protective effects… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: The estimation of HIV incidence, or the rate of new infections in a population, is an important public health indicator that provides valuable information on the growth of the epidemic and the efficacy of various intervention strategies. Within the past 15 years, a new strategy for… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: Although substantial progress has been made to identify new biomedical HIV prevention strategies, including topical and oral antiretroviral drug pre-exposure prophylaxis (PrEP) regimens and vaccines, they are not yet approved for general use. However, these preventions (or related… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: The currently licensed oral rotavirus vaccines Rotarix™ and Rotateq™ are effective in reducing cases of severe diarrhea among children in high and middle income countries, but are significantly less effective in low income countries. In addition, both vaccines are associated with a… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: Vaccines are one of the most powerful tools available for preventing disease. Measles vaccine has led to the elimination of endemic measles from the Western Hemisphere and a tremendous reduction in global mortality. However, the logistic difficulties inherent in vaccination by injection… more
Agency: HHS
Solicitation: PHS 201301 Open Period: 15-Aug-2012 to 03-Dec-2012
Topic Description: Background: CDC has both domestic and international laboratory programs that provide clinical specimen testing for the detection of known and emerging infections, chemical, or radiological agents that pose global health threats. Current methods for collection, storage, and transport of biological… more
Displaying 1971 – 1980 of 3738 Topics
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