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ENZYMATIC LUMINESCENCE microRNA ASSAY

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
85428
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
CA126647
Solicitation Year:
N/A
Solicitation Topic Code:
NCI
Solicitation Number:
N/A
Small Business Information
SCI-TEC, INC.
10425 COGDILL RD. #300 KNOXVILLE, TN -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2010
Title: ENZYMATIC LUMINESCENCE microRNA ASSAY
Agency: HHS
Contract: 2R44CA126647-03
Award Amount: $760,166.00
 

Abstract:

DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective RNA Enzymatic Luminescence Assay (qELA) for high-throughput detection and quantification of microRNA in biological samples. The assay impl ements the same detection concept known from pyrosequencing, yet expanding pyrosequencing detection methodology for highly sensitive and accurate quantification of small RNA molecules. The proposed assay can match the performance of the real time quantitat ive PCR technique (rt-qPCR) in many applications and is simpler and more cost effective. The technology can be implemented in a number of commercial assays for application in life science research, drug discovery, and clinical diagnosis. PUBLIC HEAL TH RELEVANCE: The goal of this project is to develop a new high performance cost effective bioluminescence assay for microRNA analysis. The proposed assay provides technologically advanced and significantly less expensive alternative for real time polymera se chain reaction technology, which currently dominates in the market. The proposed bioluminescent assay is universal and can be used in various applications in life science research, drug discovery, clinical diagnosis by 1,800 clinical laboratories and th ousands of life science research laboratories in US.

Principal Investigator:

Ye Sun
8656712166
YE_SUN@SCIEN-TEC.COM

Business Contact:

Ye Sun
golovlev@scien-tec.com
Small Business Information at Submission:

SCI-TEC, INC.
SCI-TEC, INC. 10425 COGDILL RD, #300 KNOXVILLE, TN -

EIN/Tax ID: 162158412
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No