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Company Information:

Company Name:
ATOM SCIENCES, INC.
Address:
ATOM SCIENCES, INC.
114 RIDGEWAY CTR
OAK RIDGE, TN 37830 8810
Phone:
N/A
URL:
N/A
EIN:
621102077
DUNS:
48900880
Number of Employees:
N/A
Woman-Owned?:
No
Minority-Owned?:
No
HUBZone-Owned?:
No

Commercialization:

Has been acquired/merged with?:
N/A
Has had Spin-off?:
N/A
Has Had IPO?:
N/A
Year of IPO:
N/A
Has Patents?:
N/A
Number of Patents:
N/A
Total Sales to Date $:
$ 0.00
Total Investment to Date $
$ 0.00
POC Title:
N/A
POC Name:
N/A
POC Phone:
N/A
POC Email:
N/A
Narrative:
N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $3,851,329.00 53
SBIR Phase II $7,010,306.00 17

Award List:

DEVELOPMENT OF SPUTTER-INITIATED RESONANCE IONIZATION SPECTROSCOPY FOR APPLICATION IN THE SINGLE-ATOM DETECTION OF TECHNETIUM

Award Year / Program / Phase:
1983 / SBIR / Phase I
Award Amount:
$45,000.00
Agency:
DOE
Principal Investigator:
Tom J. Whitaker
Abstract:
N/a

DEPTH POFILING IN ALGAAS AND LINOO3 USING SPUTTER INITIATED RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1983 / SBIR / Phase I
Award Amount:
$49,470.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Abstract:
N/a

DEPTH POFILING IN ALGAAS AND LINOO3 USING SPUTTER INITIATED RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1984 / SBIR / Phase II
Award Amount:
$185,000.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Abstract:
We propose the extension of a new analytical technique, sputter initiated resonance ionization spectroscopy (siris) to include depth profiling. this phase i project will determine the feasibilty of making this preliminary measurements using the siris technique on standard samples of si doped algaas… More

DEVELOPMENT OF SPUTTER-INITIATED RESONANCE IONIZATION SPECTROSCOPY FOR APPLICATION IN THE SINGLE-ATOM DETECTION OF TECHNETIUM

Award Year / Program / Phase:
1984 / SBIR / Phase II
Award Amount:
$439,119.00
Agency:
DOE
Principal Investigator:
Tom J. Whitaker
Abstract:
We propose the development of a new analytical technique, sputter-initiated resonance ionization spectroscopy (siris) for the single-atom detection of isotopes of technetium. this technique is to be used in a study recently proposed by g.a. cowan and w.c. haxton to determine the boron-8 component of… More

AND KRYPTON-85 ATOM COUNTING

Award Year / Program / Phase:
1986 / SBIR / Phase I
Award Amount:
$49,789.00
Agency:
DOE
Principal Investigator:
Dr. norbert thonnard , PRINCIPAL INVESTIGATOR
Abstract:
In the disposal of hazardous wastes, attention must be directed not only to the problems of safe collection, transportation and storage, but also to the problem of isolating the hazardous material for a long time. this is especially true for radioactive wastes, which need to be isolated for many… More

ULTRA-TRACE MATERIALS ANALYSIS USING RIS

Award Year / Program / Phase:
1986 / SBIR / Phase I
Award Amount:
$55,407.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Dr norbert thonnard
Abstract:
Requirements for material characterization are becoming more stringent as the role of the trace element composition of hightechnology devices becomes apparent. in semiconductor research, for instance, there is a need for ultra-trace element analysis in solids below the ppba level with spatical… More

GENERALIZED DETECTORS: ISOTOPICALLY SELECTIVE SINGLE ATOM COUNTING OF NOBLE GASES

Award Year / Program / Phase:
1986 / SBIR / Phase I
Award Amount:
$49,868.00
Agency:
DOE
Principal Investigator:
Dr. Norbert Thonnard , Principal Investigator
Abstract:
N/a

NEONATAL NUTRITION AND RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1986 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Larry J Moore , Principal Investigator
Abstract:
N/a

TRACE ELEMENT CHARCTERIZATION IN III-V COMPOUNDS BY SPUTTER INITIATED RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1986 / SBIR / Phase I
Award Amount:
$49,782.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Dr James E Parks
Abstract:
N/a

TRACE ELEMENT CHARCTERIZATION IN III-V COMPOUNDS BY SPUTTER INITIATED RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1987 / SBIR / Phase II
Award Amount:
$167,585.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Dr James E Parks
Abstract:
The vlsi and vhisc development programs of the air force require characterization of iii-v compounds with an interference free, highly sensitive element analysis technique having good lateral and depth resolution. sputter initiated resonance ionization spectroscopy (siris), an ultrasensitive… More

GENERALIZED DETECTORS: ISOTOPICALLY SELECTIVE SINGLE ATOM COUNTING OF NOBLE GASES

Award Year / Program / Phase:
1987 / SBIR / Phase II
Award Amount:
$238,702.00
Agency:
DOE
Principal Investigator:
Dr. Norbert Thonnard , Principal Investigator
Abstract:
Resonance ionization spectroscopy (ris) is proposed as a newmethod for counting individual atoms of the noble gases ar, kr, and xe with isotopic selectivity. ris involves the stepwise excitation, ionization, and counting of atoms of a pre-selected element, generally in a large background of other… More

NEONATAL NUTRITION AND RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1987 / SBIR / Phase II
Award Amount:
$261,000.00
Agency:
HHS
Principal Investigator:
Larry J Moore , Principal Investigator
Abstract:
A paucity of knowledge exists about neonatal trace element nutrition requirements, especially for premature infants, whose critical final trimester accumulation of essential trace elements is abruptly ceased at birth. the objective of this proposal is to develop the science and technology "bridge"… More

TRACE CHROMIUM IN DIABETES USING RESONANCE IONIZATION

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Larry j moore phd
Abstract:
Trace element nutriture is increasingly acknowledged as a key aspect of growth, development, and health. trace chromium may be related to regulation of insulation action, restoration of impaired glucose tolerance, and the causal

IMPROVED SENSITIVITY AND SELECTIVITY IN COLLECTOR PROBE EXPERIMENTS BY ANALYSIS WITH RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$49,892.00
Agency:
DOE
Principal Investigator:
Dr norbert thonnard
Abstract:
In the fusion energy program, collector probes are an important tool for characterizing and understanding the particle fluxes and energies in the plasma edge. the energyof the ions and neutral atoms impinging on these probes is quite low, thereby leaving most of the particles close to the probe… More

IMAGING OF ELEMENTS IN TISSUE AT TRACE CONCENTRATIONS

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Norbert thonnard phd
Abstract:
Instrumentation enabling quantitative trace element-concentration imaging with high sensitivity and resolution (1 ppm, 5 ) of biological tissue sections over 2x2mm(2) would be a valuable research tool. simultaneous structural imaging would enhance its utility. sputter-initiated resonance ionization… More

SUBPICOSECOND DESORPTION AND MASS ANALYSIS OF LARGE MOLECULES

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Larry j moore
Abstract:
Emerging health and medical research problems are placing stringent requirements on the ability to characterize labileand high-molecular-weight organic compounds. in biotechnology, for example, intermediate synthesis products must be identified. recent ion bombardment desorption models suggest that… More

SILICON DETERMINATION FOR NUTRITION WITH RESONANCE IONIZATION MASS SPECTROMETRY

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$49,928.00
Agency:
USDA
Principal Investigator:
Dr Larry J Moore
Abstract:
N/a

CHROMIUM DEFICIENCY IN INSULIN RESISTANCE

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$49,951.00
Agency:
HHS
Principal Investigator:
Larry J Moore
Abstract:
N/a

SILICON DETERMINATION FOR NUTRITION WITH RESONANCE IONIZATION MASS SPECTROMETRY

Award Year / Program / Phase:
1988 / SBIR / Phase II
Award Amount:
$150,000.00
Agency:
USDA
Principal Investigator:
Dr Larry J Moore
Abstract:
Silicon may have metabolic roles in atherosclerotic disorders, connective tissue and bone formation, morphogenesis in primitive cells and the aging process. however, little is known about the role of silicon in human nutrition and metabolism. the absence of a reliable analytical tool for trace and… More

AN ATOM CLUSTER ION DESORPTION SOURCE

Award Year / Program / Phase:
1988 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Abstract:
The need to characterize complex organic compounds for biotechnology applications, such as protein sequencing, has placed stringent requirements on the development of characterization tools. recent developments in cluster ion formation and ion bombardment desorption theory suggest thatcluster ion… More

ALUMINUM IN BRAIN DISEASES

Award Year / Program / Phase:
1988 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Abstract:
Aluminum has been implicated in neurological and aging disorders, including alzheimer's disease and dialysis dementia. previous trace analysis studies were subject to interferences and contamination, and lacked elemental specificity, sensitivity, and isotopic information. resonance ionization… More

RED BLOOD CELL MEASUREMENTS USING RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1988 / SBIR / Phase I
Award Amount:
$49,957.00
Agency:
NASA
Principal Investigator:
Larry J Moore
Abstract:
N/a

RED BLOOD CELL MEASUREMENTS USING RESONANCE IONIZATION SPECTROSCOPY

Award Year / Program / Phase:
1989 / SBIR / Phase II
Award Amount:
$485,710.00
Agency:
NASA
Principal Investigator:
Larry J Moore
Abstract:
Astronauts and animals flown in microgravity have experienced a loss of red blood cell mass, but mechanisms causing this phenomenon are not understood. preparations for in-flight hematology studies include a desire to eliminate radioactive tracers and substitute safe stable isotopes. realistic… More

ULTRASENSITIVE NICKEL DETERMINATIONS FOR TOXICOLOGY

Award Year / Program / Phase:
1989 / SBIR / Phase I
Award Amount:
$49,917.00
Agency:
HHS
Principal Investigator:
Abstract:
Increasingly stringent requirements are being placed on the detection and accurate characterization of toxic elements inenvironmental health. the toxicology of nickel, in elemental and metallo-organic form, has been the subject of much attention in recent years. nickel has been implicated in… More

SENSITIVE PERSONNEL DOSIMETRY OF 3KEV TO 20MEV NEUTRONS

Award Year / Program / Phase:
1989 / SBIR / Phase I
Award Amount:
$44,958.00
Agency:
HHS
Principal Investigator:
Abstract:
A fast neutron dosimeter is planned that would be used by personnel involved in research or medical treatment with neutrons, and would thus satisfy some of the needs of the national cancer institute (nci). the dosimeter will be sensitive to neutrons of >3-kev energy with negligible response to other… More

SPUTTER INITIATED RESONANCE IONIZATION SPECTROSCOPY FOR IN SITU MICROANALYSIS IN THE GEOSCIENCES

Award Year / Program / Phase:
1989 / SBIR / Phase I
Award Amount:
$49,680.00
Agency:
NSF
Principal Investigator:
Robert D Willis , Principal Investigator
Abstract:
Sputter initiated resonance ionization spectroscopy (siris),based on the concept of resonance ionization of sputtered atoms, offers the potential to make in situ chemical and isotopic microanalyses with excellent sensitivity, minimal fractionation and matrix effects, and freedom from isobaric… More

INCREASED SPEED IN DNA SEQUENCING BY UTILIZING LARIS TO LOCALIZE MULTIPLE STABLE ISOTOPE LABELED FRAGMENTS

Award Year / Program / Phase:
1989 / SBIR / Phase I
Award Amount:
$49,947.00
Agency:
DOE
Principal Investigator:
Dr Heinrich F Arlinghaus , Principal Investigator
Abstract:
N/a

INCREASED SPEED IN DNA SEQUENCING BY UTILIZING LARIS TO LOCALIZE MULTIPLE STABLE ISOTOPE LABELED FRAGMENTS

Award Year / Program / Phase:
1990 / SBIR / Phase II
Award Amount:
$494,436.00
Agency:
DOE
Principal Investigator:
Dr Heinrich F Arlinghaus , Principal Investigator
Abstract:
Mapping and sequensing the dna in the human genome is of crucial importance to future medical advances and economic competitiveness. utilization of dna probes labeled with dozens of stable isotopes instead of a single radioisotope could increase the rate of sequence determination 100-fold or more… More

KRYPTON-81 DATING IN POLAR ICE SAMPLES

Award Year / Program / Phase:
1990 / SBIR / Phase I
Award Amount:
$49,931.00
Agency:
NSF
Principal Investigator:
Robert D Willis , Senior Scientist
Abstract:
Air bubbles trapped in polar ice at the time of ice formation provide valuable clues to aid in our understandingof the causes of global climate change. it is vital in thiseffort that the age of the ice (which may be 500,000 yrs. ormore in some locations) be established. presently, there isno method… More

MEASUREMENT OF CARBON 14 ISOTOPICALLY SELECTIVE RESONANCE IONIZATION MASS SPECTROSCOPY

Award Year / Program / Phase:
1990 / SBIR / Phase I
Award Amount:
$49,750.00
Agency:
NSF
Principal Investigator:
Michael C Wright , Scientist
Abstract:
(14)c dating by means of radioactive decay counting, and recently by means of tandem accelerator mass spectrometer (tams) is extremely important in a wide range of fields including anthropology, archaeology, hydrology, oceanography, and others. proposed here is a new method forcounting (14)c or,… More

DNA SEQUENCING BY HYBRIDIZATION ON SURFACES: DEVELOPMENT OF ULTRA-SENSITIVE TWO-DIMENSIONAL DETECTORS

Award Year / Program / Phase:
1990 / SBIR / Phase I
Award Amount:
$49,390.00
Agency:
DOE
Principal Investigator:
Abstract:
The need to map and sequence dna in the human genome is of crucial importance for a better understanding of genetics and disease processes. current dna sequencing procedures almost universally require gel electrophoresis of dna fragments, and several laboratories are devising procedures to automate… More

OIL-FIELD RESERVOIR CHARACTERIZATION WITH ORDER-OF-MAGNITUDE DYNAMIC RANGE IMPROVEMENT IN TRACER DETECTABILITY

Award Year / Program / Phase:
1990 / SBIR / Phase I
Award Amount:
$49,447.00
Agency:
DOE
Principal Investigator:
Abstract:
The use of tracers to tag well gas which is reinjected into oil reservoirs has achieved considerable success in characterizing the structure and geometry of the reservoirs. ideally, the tracer should be detectable over a wide dynamic range, particularly in fields where large volumes of gas are… More

CHROMIUM DEFICIENCY IN INSULIN RESISTANCE

Award Year / Program / Phase:
1990 / SBIR / Phase II
Award Amount:
$499,351.00
Agency:
HHS
Principal Investigator:
Larry J Moore
Abstract:
Chromium deficiency causes severe insulin resistance and glucose intolerance. average dietary chromium intake in theunited states and other developed countries is marginal and may contribute to the high frequency of diabetes plaguing developed countries. the major clinical chromium evaluationproblem… More

QUANTITATIVE AND SENSITIVE PROFILING OF DOPANTS AND IMPURITIES IN COMPOUND SEMICONDUCTORS USING ...

Award Year / Program / Phase:
1990 / SBIR / Phase I
Award Amount:
$50,000.00
Agency / Branch:
DOD / DARPA
Principal Investigator:
Heinrich Arlinghaus
Abstract:
N/a

NEW CONCEPTES IN ULTRASENSITIVE NOBLE GAS DETECTION FOR OCEAN SCIENCE APPLICATIONS

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
NSF
Principal Investigator:
Robert D. Willis , Senior Scientist
Abstract:
Cosmogenic argon-39 is ideally suited for studying the penetration of greenhouse gases across the thermocline and for studying deep-ocean circulation. the need for large samples and long decay-counting times due to its low concentration has greatly limited the application of this important tracer.… More

DEVELOPMENT OF MICRON TO SUBMICRON THICKNESS ELECTROPHORESISGELS TO OPTIMIZE RESOLUTION IN DNA SEQUENCING USING RIS

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$49,963.00
Agency:
DOE
Principal Investigator:
Dr Heinrich F Arlinghaus , Principal Investigator
Abstract:
Typically, dna sequencing is accomplished using electrophoresis gels several hundred microns thick, because these gels transport the necessary concentration of dna fragment markers (fluorescent or radioactive), and because the technology for utilizing these gels is mature. recent work has shown that… More

MICROMETER SPATIAL RESOLUTION IN SENSITIVE AND QUANTITATIVE BORON IMAGING OF TISSUES IN BORON NEUTRON CAPTURE THERAPY USING LARIS

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
DOE
Principal Investigator:
Dr Heinrich F Arlinghaus , Principal Investigator
Abstract:
Chemical and immunological therapies for cancer offer promise for controlling limited numbers of systemically dispersed tumor cells; however, localized treatment modalities are required for many tumor types that are unresponsive to current therapies. brain tumors, which are protected by the… More

IMAGING OF BORON IN TISSUE AT CELLULAR LEVEL FOR BNCT

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$49,927.00
Agency:
HHS
Principal Investigator:
Arlinghaus, Heinrich F , Principal Investigator
Abstract:
Boron neutron capture therapy (bnct) is conducted by loading boron biochemically into a tumor and irradiating with thermal neutrons. since the ranges of the alpha particles and lithium ions that result from the capture are very short (mum), the clinical efficacy is only guaranteed if this boron is… More

ULTRA SENSITIVE ANALYSIS FOR PT BY RIS IN TUMOR THERAPY

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Taylor, Ellison H , Principal Investigator
Abstract:
The platinum compound cisplatin is widely used in the treatment of solid tumors. practical problems of toxicity, decreasing efficacy over time and other s arise, and can be attacked most effectively through a better knowledge of the various mechanisms involved, requiring the ability to measure the… More

OPTIMIZATION OF ELECTROPHORESIS GELS FOR RIS ANALYSIS

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$49,095.00
Agency:
HHS
Principal Investigator:
Arlinghaus, Heinrich F , Principal Investigator
Abstract:
Given a fast, sensitive detection method, a large number of stable isotopes could be used to label dna, thereby multiplexing the separation process, and providing a new, much faster procedure for localizing dna after electrophoresis. sputter-initiated resonance ionization spectroscopy (siris) can be… More

QUANTITATIVE AND SENSITIVE PROFILING OF DOPANTS AND IMPURITIES IN COMPOUND SEMICONDUCTORS USING ...

Award Year / Program / Phase:
1992 / SBIR / Phase II
Award Amount:
$297,888.00
Agency / Branch:
DOD / DARPA
Principal Investigator:
Heinrich Arlinghaus
Abstract:
The development of an analytical technique having high depth and lateral resolution, very high sensitivity and selectivity, very high (>10 x12) dynamic range, high quantitation accuracy, and independence from matrix effects on surfaces and at interfaces, is critical in many areas of research,… More

TRACE BORON QUANTITATION IN PITUITARY TISSUES FOR BORON NEUTRON

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$49,993.00
Agency:
HHS
Principal Investigator:
Ellison H Taylor
Abstract:
N/a

TRACE BORON QUANTITATION IN PITUITARY TISSUES FOR BORON NEUTRON

Award Year / Program / Phase:
1993 / SBIR / Phase II
Award Amount:
$500,000.00
Agency:
HHS
Principal Investigator:
Ellison H Taylor
Abstract:
Pituitary tumors comprise about ten percent of all brain tumors. the clinical presentation of these tumors is diverse, the morbidity and mortality is high, and the treatment modalities are inadequate. loading pituitary corticotrophs and somatotrophs with 10boron linked to either corticotrophin… More

UV-B DETECTOR BASED UPON RYDBERG STATES

Award Year / Program / Phase:
1993 / SBIR / Phase I
Award Amount:
$49,981.00
Agency:
USDA
Principal Investigator:
Dr Tom J Whitaker
Abstract:
The threat of ozone depletion causing increased ultraviolet radiation at mid-latitudes on the earth's surface, and the resulting harm to plant and animal life, have promoted the u.s. department of agriculture to establish an improved uv irradiance monitoring program, with emphasis on the uv-b… More

Genosensor Matrices for Genome Mapping and Sequencing

Award Year / Program / Phase:
1994 / SBIR / Phase I
Award Amount:
$76,014.00
Agency:
HHS
Principal Investigator:
Heinrich Arlinghaus
Abstract:
This project will use sequencing by hybridization (SBH) to develop a faster, more economicalmethod for sequencing and mapping. Current DNA sequencing procedures almost universally require gelelectrophoresis of DNA fragments and are cumbersome and slow. SBH promises to produce rapidly largeamounts of… More

IN SITU SPUTTER-INITIATED RESONANCE IONIZATION MICROPROBE ANALYSIS OF ISOTOPIC COMPOSITIONS AND ELEMENTAL ABUNDANCES FOR GEOCHEMISTRY AND COSMOCHEMISTRY

Award Year / Program / Phase:
1994 / SBIR / Phase I
Award Amount:
$64,994.00
Agency:
NSF
Principal Investigator:
Heinrich F Arlinghaus
Abstract:
Researchers are demonstrating the potential applicability of the sputter-initiated resonance ionization microprobe (sirimp) technique for geological studies by measuring pb isotope ratios and u/pb atomic ratios in geological samples relevant to geochronology. sirimp is based on the concept of… More

Optimizing Electrophoresis Gels for Rimp Analysis

Award Year / Program / Phase:
1994 / SBIR / Phase I
Award Amount:
$80,998.00
Agency:
HHS
Principal Investigator:
Heinrich Arlinghaus
Abstract:
N/a

Optimizing Electrophoresis Gels for Rimp Analysis

Award Year / Program / Phase:
1995 / SBIR / Phase II
Award Amount:
$500,000.00
Agency:
HHS
Principal Investigator:
Heinrich Arlinghaus
Abstract:
This project uses sequencing by hybridization to develop a new method to detect mutations,allowing disease diagnoses in selected genes from a large number of individuals, in a faster, moreeconomical and more comprehensive way than can currently be accomplished. Stable isotopes is utilizedas DNA… More

A New Nanoprobe Instrument for Imaging Trace Elements in Electronic and Optoelectronic Devices

Award Year / Program / Phase:
1995 / SBIR / Phase I
Award Amount:
$64,994.00
Agency:
NSF
Principal Investigator:
Heinrich Arlinghaus
Abstract:
N/a

A New Instrument for Quantitive Measurements of High-Ionization Thereshold Elements in Nanostructures

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$98,992.00
Agency / Branch:
DOD / DARPA
Principal Investigator:
Heinrich Arlinghaus
Abstract:
The objective of the project is to develop a new mass spectrometric diagnostic tool that will allow quantitative measurement on a nanometer scale of elements having a high ionization potential, such as hydrogen, carbon, nitrogen, oxygen fluorine, and phosphorous. The proposed work would extend the… More

A New Nanoprobe Instrument for Imaging Trace Elements in Electronic and Optoelectronic Devices

Award Year / Program / Phase:
1997 / SBIR / Phase II
Award Amount:
$299,982.00
Agency:
NSF
Principal Investigator:
Heinrich Arlinghaus
Abstract:
N/a

ECR PLASMA MASS SPECTROMETRY FOR C14 AND H3 DETECTION

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$99,873.00
Agency:
HHS
Principal Investigator:
Guo, xiao q
Abstract:
N/a

SBIR Phase I: A New Instrument for Surface Characterization

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$74,605.00
Agency:
NSF
Principal Investigator:
Xiao-Qin Guo
Abstract:
N/a

SEQUENCING BY HYBRIDIZATION WITH UNLABELED DNA

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$99,794.00
Agency:
HHS
Principal Investigator:
Arlinghaus, heinrich f
Abstract:
N/a

MOLECULAR IMAGING WITH SUBCELLULAR RESOLUTION

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$99,050.00
Agency:
HHS
Principal Investigator:
Whitaker, tom j
Abstract:
N/a

A Quantitative Analytical Tool for Producing DNA-Based Diagnostic Arrays

Award Year / Program / Phase:
1998 / SBIR / Phase I
Award Amount:
$74,993.00
Agency:
DOE
Principal Investigator:
Dr. Tom J. Whitaker , President
Abstract:
50476-98-I A Quantitative Analytical Tool for Producing DNA-Based Diagnostic Arrays--Atom Sciences, Inc., 114 Ridgeway Center, Oak Ridge, TN 37830-6926; (423) 483-1113 Dr. Tom J. Whitaker, Principal Investigator Dr. Tom J. Whitaker, Business Official DOE Grant No. DE-FG02-98ER82536 Amount: … More

SBIR Phase I: A New Instrument for Surface Characterization

Award Year / Program / Phase:
1998 / SBIR / Phase II
Award Amount:
$399,810.00
Agency:
NSF
Principal Investigator:
Xiao-Qin Guo
Abstract:
N/a

N/A

Award Year / Program / Phase:
1999 / SBIR / Phase II
Award Amount:
$560,566.00
Agency:
DOE
Principal Investigator:
Dr Tom J Whitaker , President
Abstract:
N/a

DNA Diagnostics Using Electrical Detection

Award Year / Program / Phase:
1999 / SBIR / Phase I
Award Amount:
$99,865.00
Agency:
DOE
Principal Investigator:
Abstract:
Not Available The proposed research seeks to develop new constant force brush holders incorporating pseudoelastic alloys for use with advanced metal foil and fiber brushes. The new brush holders satisfy requirements relevant to brush pressure and wear movements; they are also compact, resistant to… More

Screening Digestive Diseases with Microcantilever Arrays

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$97,295.00
Agency:
HHS
Principal Investigator:
Michael S. Kriger
Abstract:
DESCRIPTION (Applicant's Abstract): The proposed research is focused on developing a low-cost diagnostic technology to screen for digestive diseases in a clinical setting. The goal is to incorporate screening for multiple diseases into a single test. Our approach is based… More

Inexpensive Genetic Detection of Infectious Organisms

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$100,758.00
Agency:
HHS
Principal Investigator:
Tom J. Whitaker
Abstract:
DESCRIPTION (Applicant's abstract): The proposed project is aimed at developing a very inexpensive and rapid diagnostic test that can be used to identify specific infectious organisms. The goal is to make the cost so low that managed health organizations would encourage its… More

RNA-Based Microbial Community Structure Determination

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$99,997.00
Agency:
DOE
Principal Investigator:
Abstract:
70524 In order to predict the bioremediation rate and ecological impact of contaminated sites, a rapid method to determine the microbial community structure is needed. Current approaches are time consuming, labor intensive, and expensive. Microarray gene probe technology exhibits… More

SNP DETECTION WITH UNLABELED, UNAMPLIFIED TARGET DNA

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$99,427.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The goal of the proposed project is to develop an analytical tool for large-scale detection of single-nucleotide polymorphisms (SNPs) in unlabeled, unamplified genomic or pooled nucleic acid samples. A dual hybridization utilizing a labeled, peptide nucleic acid… More

SNP Detection with Unlabeled, Unamplified Target DNA

Award Year / Program / Phase:
2003 / SBIR / Phase II
Award Amount:
$759,216.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The aim of the research project is to further develop the dual hybridization diagnostic genotyping method into a multiplex assay capable of using unlabeled, unamplified DNA as the target. The feasibility of the dual hybridization method was demonstrated in Phase… More

Inexpensive Genetic Detection of Infectious Organisms

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$0.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a… More

Inexpensive Genetic Detection of Infectious Organisms

Award Year / Program / Phase:
2003 / SBIR / Phase II
Award Amount:
$771,941.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a… More

Specific Diagnostic for Members of Genus Mycobacterium

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$99,998.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): A novel microarray-based system is proposed for diagnosis of tuberculosis and tuberculosis-like respiratory infections. This diagnostic system offers a parallel method to screen clinical samples for the presence of DNA sequences from Mycobacterium tuberculosis,… More

Bioagent Characterization by Iterative Extension

Award Year / Program / Phase:
2006 / SBIR / Phase I
Award Amount:
$606,491.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Project Summary - A new syndrome-based diagnostic system for rapid detection and identification of category B and C priority pathogens is proposed. Phase 1 will focus on V. cholerae genes and genes from similar pathogens. The technique relies upon a… More

Analysis of Environmental Mycobacterium Ulcerans

Award Year / Program / Phase:
2007 / SBIR / Phase I
Award Amount:
$98,841.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The aim of this research is to develop a locus-specific DNA amplification process suitable for highly multiplexed detection of pathogenic mycobacteria in environmental samples. Specifically, this project aims to develo p an assay to identify the presence of… More

Ultra-Sensitive Molecular Diagnostic for Borrelia Species

Award Year / Program / Phase:
2008 / SBIR / Phase I
Award Amount:
$73,327.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The aim of the proposed research is to develop an enabling technology that will allow development of a molecular diagnostic for identification and discrimination among closely related bacterial species that cause signif icant disease at low microorganism numbers.… More