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Neuromonitoring of Traumatic Brain/blast Injury

Award Information

Department of Defense
Office of the Secretary of Defense
Award ID:
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
OSD 09-H06
Solicitation Number:
Small Business Information
Advanced Brain Monitoring
2237 Faraday Ave Suite 100 Carlsbad, CA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2010
Title: Neuromonitoring of Traumatic Brain/blast Injury
Agency / Branch: DOD / OSD
Contract: W81XWH-10-C-0061
Award Amount: $99,973.00


It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the strategy of resuscitation and acute care, and therefore contribute to a substantially improved survival and functional outcome. We propose to develop a small, light-weight, battery powered and hand-portable 3-channel monitor that combines electro- and rheoencephalography (EEG and REG). While REG detects changes in cerebral vascular bed, EEG can be used to detect post-traumatic non-convulsive seizures or reversible breakdown of the synaptic transmission. The monitor consists of a smaller (2 x 2 x 0.5 in) wearable unit for data acquisition and a larger (7 x 5 x 0.8) unit for visualization and storage of data. The units communicate to each other wirelessly, via a Bluetooth link, or through a cable. The larger unit processes the incoming data in real time, and warns clinicians (via an audio alarm) of a deterioration of the patient''s condition. The bigger unit can connect to a LAN or the internet so that the REG/EEG data can be downloaded and analyzed offline by clinicians.

Principal Investigator:

Djordje Popovic
Director of Research

Business Contact:

Christine Berka
Chief Executive Officer
Small Business Information at Submission:

Advanced Brain Monitoring
2237 Faraday Ave Suite 100 Carlsbad, CA 92008

EIN/Tax ID: 330886301
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No