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High-Throughput Brain Injury Proteomic Microassay

Award Information

Agency:
Department of Defense
Branch:
Office of the Secretary of Defense
Award ID:
76632
Program Year/Program:
2005 / STTR
Agency Tracking Number:
O054-003-2011
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BANYAN BIOMARKERS, INC.
12085 RESEARCH DR ALACHUA, FL 32615-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2005
Title: High-Throughput Brain Injury Proteomic Microassay
Agency / Branch: DOD / OSD
Contract: W81XWH-05-C-0168
Award Amount: $99,685.00
 

Abstract:

Traumatic brain injury (TBI) is a leading cause of combat casualty. Previous estimates for 20th century conflicts were that 15 - 25% of all injuries were sustained to the head. However, with the increased incidence of blast injuries that military personnel are suffering in the current conflicts in Afghanistan and Iraq, head injury is becoming an even more frequent occurrence. Far forward medics need a device to objectively and quantifiably diagnose brain injury in order to effectively triage and provide appropriate treatment to their casualties, thereby providing for improved long-term outcome. The overall objective of this STTR topic is to develop a hand-held point-of-care device for analyzing biomarkers of brain injury that can be used as a diagnostic and triage tool by military medics on the battlefield. This Phase I proposal will establish the feasibility of adapting standard Enzyme-linked immunosorbent assays (ELISAs) of three brain injury biomarkers into an automated miniaturized, multiplexed assay panel using antibody microarray technology. The proposal combines the expertise of the University of Florida in identifying and validating biomarkers of brain injury, of Banyan Biomarkers in developing and optimizing ELISAs for these biomarkers, and of Clinical Microarrays (CMA) in adapting ELISA technology into their patented biochip format.

Principal Investigator:

Monika Oli
Senior Scientist
3864181632
moli@banyanbio.com

Business Contact:

Ken Walz
Chief Fiancial Officer
4103579485
kwalz@banyanbio.com
Small Business Information at Submission:

Daimonion Diagnostics, Llc
12085 Research Drive Alachua, FL 32615

EIN/Tax ID: 020573903
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIV. OF FLORIDA
PO Box 100256
Gainesville, FL 32610
Contact: Kevin Wang
Contact Phone: (352) 392-3681
RI Type: Nonprofit college or university