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Regional Flow Imaging by Fluorescent Microspheres

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
22340
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
22340
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BARLOW SCIENTIFIC, INC.
6307 TAMOSHAN DR NW OLYMPIA, WA 98502-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1995
Title: Regional Flow Imaging by Fluorescent Microspheres
Agency: HHS
Contract: N/A
Award Amount: $596,945.00
 

Abstract:

We will develop a new approach to the evaluation of microregional circulation. This research is based on the working hypothesis that fluorescent microspheres can be spatially located by fluorescence imaging of organ serial sections. The project will develop instrumentation and procedures to evaluate regional flow in an entire organ. During Phase I, a computer-controlled imaging system will be assembled and images of fluorescent microspheres embedded in perfused rat hearts will be taken. Data analysis procedures will be developed to determine microregional flow characteristics. Phase I studies will demonstrate the feasibility of the working hypothesis and provide design parameters for imaging systems to be constructed during Phase II for use with larger hearts. This project will provide researchers with the instrumentation to rapidly and automatically evaluate microregional flow in tissue using the same procedures involved in radioactive microsphere flow determinations.

Principal Investigator:

Clyde H. Barlow
2068661244

Business Contact:

Small Business Information at Submission:

Barlow Scientific
6307 Tamoshan Drive, NW Olympia, WA 98502

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No