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A High-Performance Food Pathogen Detection Instrument

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
65526
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
RR018420
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BIODETECTION INSTRUMENTS, LLC
535 W Research Blvd., Suite 135, M/S 300 FAYETTEVILLE, AR 72701-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2003
Title: A High-Performance Food Pathogen Detection Instrument
Agency: HHS
Contract: 1R43RR018420-01
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Food safety remains a critical issue for human health in our society. The food system in our nation is vulnerable to contamination from natural pathogens and from bio-terrorist attack. Current detection methods are inadequate due to the time-consuming and laboratory-centered approaches presently in use. Instruments for rapid on-site detection of pathogens in food are urgently needed. The objective of this project is to evaluate an innovative capillary bioseparator / bioreactor-based optical biosensor technology for rapid detection of E. coli O157:H7. The detection limit, specificity and detection time possible with this approach will be evaluated. It is expected that the technology will provide <100 cells/ml detection limit, <1 h detection time, and high specificity to E. coli O157:H7 (<1% false positive/negative data). Although the initial work will focus on food safety, similar technology can be utilized for rapid, on-site screening of human E. coli infections. Rapid screening of human infections is also very important because life-threatening E. coli infections are increasing especially in susceptible groups such as premature babies. Preliminary data indicate that the proposed approach has good potential to significantly improve the state-of-the-art in rapid, sensitive, and specific detection of E. coli O157:H7 and eventually other biological pathogens.

Principal Investigator:

Xiaoli Su
4795712592
XSU@VIRTUAL-INCUBATION.COM

Business Contact:


4795712592
Small Business Information at Submission:

BIODETECTION INSTRUMENTS, INC.
21 WEST MOUNTAIN SUITE 122, M/S 300 FAYETTEVILLE, AR 72701

EIN/Tax ID: 113682219
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No