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Injectable Microbeads for Delivery of Buprenorphine

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29312
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29312
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BEND RESEARCH, INC.
64550 RESEARCH RD BEND, OR 97701
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Injectable Microbeads for Delivery of Buprenorphine
Agency: HHS
Contract: 1 R43 DA09746-01,
Award Amount: $99,999.00
 

Abstract:

The objective of this research program is to demonstrate the feasibility of a new controlled-releasuse in an injectable formulation of buprenorphine to improve treatment of opioid dependence. The keytechnology is the use of bioerodible microporous microbeads with a controllable structure that allowas well as easily varied release rates and durations of release. These controlled-release microbeadsinjectable formulation that would result in much-improved patient compliance, better efficacy, and fthe case with current therapies. Specific tasks in Phase l include identification of bioerodible polcandidate microporous microbeads, in vitro testing of drug- loaded microbeads, determination of shorvivo evaluation of candidate microbeads in rhesus monkeys. The feasibility of this approach will bevitro and in vivo tests indicate efficacy over 3- to 14-day time periods. If this is the case, a Phaon further development of this technology and completion of preclinical studies necessary for submisInvestigational New Drug application.

Principal Investigator:

James Nightingale
50382

Business Contact:

Small Business Information at Submission:

Bend Research, Inc.
64550 Research Road Bend, OR 97701

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No