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AN IMMUNOASSAY FOR A HUMAN GROWTH HORMONE VARIANT

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7186
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7186
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Berkeley Antibody Company
4131 Lakeside Drive Suite B Richmond, CA 94806
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: AN IMMUNOASSAY FOR A HUMAN GROWTH HORMONE VARIANT
Agency: HHS
Contract: N/A
Award Amount: $42,000.00
 

Abstract:

THE OBJECTIVE OF THIS RESEARCH PROPOSAL IS TO DEVELOP ANTIBODIES CAPABLE OF DISTINGUISHING NORMAL HUMAN GROWTH HORMONE (HGH-N) FROM THE PRODUCT OF THE VARIANT GROWTH HORMONE GENE (HGH-V). PEPTIDES WILL BE SYNTHESIZED CORRESPONDING TO REGIONS OF DISSIMILARITY FROM BOTH FORMS OF THE HORMONE. THESE PEPTIDES WILL THEN BE CONJUGATED TO CARRIER MOLECULES FOR SYNTHESIS OF EFFECTIVE IMMUNOGENS AND USED TO GENERATE SPECIFIC ANTIBODIES IN RABBITS. THESE ANTIBODIES WILL BE TESTED FOR SPECIFICITY OF BINDING TO ONE FORM OF THE HORMONE OR THE OTHER. SUCH ANTIBODIES WILL BE USEFUL TO DETERMINE WHETHER OR NOT THE VARIANT GENE IS EXPRESSED IN HUMANS. IMMUNOASSAYS UTILIZING THESE HORMONES WILL HAVE EXTENSIVE UTILITY FOR THE DIAGNOSIS OF GROWTH DISORDERS IN HUMANS.

Principal Investigator:

Thomas r anderson phd
4152224940

Business Contact:

Small Business Information at Submission:

Berkeley Antibody Co
4131 Lakeside Drive Suite B Richmond, CA 94806

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No