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Mercury Fiber Electrode for Determining Lead in Blood

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
25054
Program Year/Program:
1996 / SBIR
Agency Tracking Number:
25054
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BIOANALYTICAL SYSTEMS, INC. (BASI)
BIOANALYTICAL SYSTEMS, INC. (BASI) 2701 KENT AVE WEST LAFAYETTE, IN 47906 1389
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1996
Title: Mercury Fiber Electrode for Determining Lead in Blood
Agency: HHS
Contract: 1 R43 ES06991-1,
Award Amount: $614,880.00
 

Abstract:

Childhood lead poisoning is stated to be "the nation's leading childhood environmental disease"and being able to accurately determine toxic lead concentrations from small volumes of children's bloodin an accurate and cost effective manner is a considerable challenge. This research describes a novelmercury fiber electrode that maintains the advantages of mercury as an electrode material and eliminatesthe problems associated with measurement in biological samples. This design places mercury inside asmall diameter dialysis tube which can be directly dipped into a sample or it can be put in a flow streamfor on line detection. The aims of this proposal is to characterize this electrode's performance; detectionlimits, precision and linearity of the lead ion response in the presence of interfering substances foundin blood samples such as proteins and oxygen. The results of this research could lead to a portable,automated analyzer that could be used in the field or laboratory. In addition, many procedures have beendeveloped using mercury electrodes and the analyzer could also be used to determine lead and othermetals from environmental samples. The design also may have applications as a detector for liquidchromatographs for the determination of difficult to reduce substances.

Principal Investigator:

Craig Brunlett
3174634527

Business Contact:

Small Business Information at Submission:

Bioanalytical Systems, Inc.
2701 Kent Avenue West Lafayette, IN 47906

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No