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Company Information:

Company Name: Biodesy LLC
City: Burlingame
State: CA
Zip+4: 94010-1311
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (917) 913-1492

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $400,272.00 3
SBIR Phase II $500,000.00 1

Award List:

Real-time Detection of GPCR Conformational Change

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Joshua S. Salafsky
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): A novel, optical detection system for detecting conformational change in a GPCR (G Protein-coupled receptor) has been devised. The detection system is based on second-harmonic generation, a nonlinear optical technique. Phase I specific aims are final… More

SHG for Integrin receptor drug discovery

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Joshua S. Salafsky
Award Amount: $150,272.00
Abstract:
DESCRIPTION (provided by applicant): Integrin receptors are critical cell surface proteins involved in cell adhesion and are important in tumor progression. Inhibitors of integrin receptors can be effective anti-cancer agents because they can prevent tumor adhesion and abolish integrin functions… More

SBIR Phase I: Development of a conformational screen for rapidly identifying kinase inhibitor type using SHG

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: NSF
Principal Investigator: Joshua Salafsky
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project builds on the rapid FDA approval success of recent cancer therapeutics that act on a specific conformation state of their target protein. Biodesy has developed a new optical technique, Second Harmonic Generation that measures protein… More

SBIR Phase II: Development of an SHG Instrument, Artemis QuantTM, for measuring conformational change in real time

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: NSF
Principal Investigator: Joshua Salafsky
Award Amount: $500,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will build a real-time detection instrument for conformational change. Conformational change is a change in the structure of a biomolecule such as a protein. For a given protein, different structural changes produce different… More