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MONITORING FISH VENTILATORY BEHAVIOR TO ASSESS BEHAVIORALLY AND NEURALLY…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
689
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
689
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Biological Monitoring Inc.
Po Box 184 Blacksburg, VA 24063
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1985
Title: MONITORING FISH VENTILATORY BEHAVIOR TO ASSESS BEHAVIORALLY AND NEURALLY MEDIATED EFFECTS OF CHEMICAL SUBSTANCES
Agency: NSF
Contract: N/A
Award Amount: $245,220.00
 

Abstract:

NORMAL VENTILATORY MOVEMENTS OF FISH GENERATE BIOELECTRIC POTENTIALS WHICH, WHEN PROPERLY AMPLIFIED AND FILTERED MAY BE INTERFACED TO COMPUTER BASED SYSTEMS TO FACILITATE AUTOMATED COLLECTION OF LARGE DATA BASES. WHEN FISH ARE EXPOSED TO ACUTELY AND SUBACUTELY TOXIC CONCENTRATIONS OF MANY CHEMICALS, COMMON VENTILATORY RESPONSES MAY INCLUDE CHANGES IN SIGNAL FREQUENCIES, AMPLITUDES, WAVEFORMS, AND COUGHS. TO BETTER UNDERSTAND THE MECHANISMS OF ACTION AND BEHAVIORALLY AND NEURALLY MEDIATED EFFECTS OF CHEMICAL SUBSTANCES ON FISH, THE AUTOMATION OF DATA COLLECTION IS ESSENTIAL. THE PROPOSED EFFORT ADDRESSES THIS ISSUE BY ATTEMPTING TO OVERCOME THE TECHNICAL DIFFICULTIES ASSOCIATEDWITH THIS PROBLEM. CHEMICALS WOULD BE CATEGORIZED BY THEIR STRUCTURE AND KNOWN TOXIC MECHANISMS OF ACTION TO DETERMINE THE MANNER IN WHICH EACH CATEGORY EFFETS FISH VENTILATORY BEHAVIOR.

Principal Investigator:

David Gruber

Business Contact:

Small Business Information at Submission:

Biological Monitoring Inc.
P.o. Box 184 Blacksburg, VA 24060

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No