Measurement of human iron stores can act as a clinically significant indicator of disease or potential disease. bothstorage iron overload and deficiency suggest further examination and possible therapeutic action. for example, blood loss due to colorectal cancer would result in subnormal storage… More

The pulmonary toxicity of environmental and occupational noxious particulates is often enhanced by impairment of normal clearance mechanisms prolonging their residence time in the lung. clearance mechanisms very strongly between individuals, resulting in a highly variable sensitivity to such… More

Neuromagnetism, the study of induced and spontaneous magnetic fields of the human brain, has been shown experimentally to provide a "non-invasive" technique that allows precise spatial localization of several sources whichcould not be well localized by measuring surface potentials.important… More

Magnetoencephalography (meg) is the measurement of extra- cranial magnetic fields generated by intracellular electric currents in the brain. it offers the ability to locate discrete sources of normal and pathological electrical activity with three-dimensional accuracy of a few milli- meters. current… More

Magnetoencephalography (meg) is the noninvasive magnetic measurement of electrical current within the brain which is believed to give significant new information about brain function that complements other modalities such as eeg and pet. using meg, sources of normal and pathological brain activity… More

The spontaneous magnetoencephalogram (meg) signals that are unrelated to a stimulus or a task, represent a fundamental barrier to continuing brain research. this background activity constitutes a form of interference, or "brain noise", that masks the desired weaker meg signals evoked by the… More

The recent discovery a high transition temperature superconductors (tc > or - 95k) and their subsequent preparation in thin-film opens the possibility of fabricating a practical superconducting quantum interference device (squid) from these materials. since the squid is the most sensitive detector… More

Magnetoencephalography(meg), the measurement of magnetic fields generated by electric currents in the brain, promisesto be a safe, sensitive, non-invasive procedure for the measurement and localization of normal and pathological brain function. the main objective of this proposal is to develop and… More

We propose to develop the core high temperature superconductor SQUID technology enabling the implemenation of a new diagnostic system capable of non-invasively measuring heart function. SQUID technology provides the only known means to detect the very small magnetic fields generated by abnormal… More