Fiscal Year:
2003
Title:
Unique Topical Treatment for UV-Induced Skin Cancer
Agency:
HHS
Contract:
1R43CA103378-01
Award Amount:
$119,962.00
Abstract:
DESCRIPTION (provided by applicant): The goal of this project is to develop a polymer-based vehicle for the topical delivery of caffeine to inhibit UV-induced skin cancer. Despite increased use of sun screen, skin cancer rates continue to rise. Recently, caffeine has been shown to inhibit carcinogenesis in murine models of UV-induced skin tumor formation. The polymer-based delivery system described in this proposal seeks to improve the efficacy and convenience of topically applied caffeine for this application.
To achieve this goal, the following Specific Aims will be pursued:
Aim 1. Formulate a Polymer-based Topical Delivery System Containing Caffeine
Aim 2. Evaluate the Effect of Caffeine Delivered from the Polymer-based Vehicle on
Ultraviolet Light-induced Skin Cancer Using a Mouse Model.
Small Business Information at Submission:
BIOMEDICAL DEVELOPMENT CORPORATION
BIOMEDICAL DEVELOPMENT CORP 500 SANDAU, STE 200 SAN ANTONIO, TX 78216
EIN/Tax ID:
742330067
DUNS:
N/A
Number of Employees:
N/A
Woman-Owned:
No
Minority-Owned:
No
HUBZone-Owned:
No