USA flag logo/image

An Official Website of the United States Government

Company Information:

Company Name: BIOMEDICAL RESEARCH MODELS, INC.
City: WORCESTER
State: MA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $4,102,923.00 11
SBIR Phase II $3,015,625.00 2
STTR Phase I $1,225,087.00 4

Award List:

NEW RAT MODEL OF OBESITY AND TYPE II DIABETES

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Guberski, dennis l
Award Amount: $99,904.00

CRYOPRESERVATION OF THE BB/WOR RAT

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kislauskis, edward h
Award Amount: $85,254.00

EARLY BIOMARKER CHANGES IN DIABETIC NEPHROPATHY

Award Year / Program / Phase: 1999 / STTR / Phase I
Agency: HHS
Research Institution: University of Oklahoma
Principal Investigator: Hemstreet
Award Amount: $98,990.00
RI Contact: N/A

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Edward H. Kislauskis
Award Amount: $123,148.00

THE BBZDR RAT, NEW MODEL OF OBESITY/TYPE 2 DIABETES

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Dennis L. Guberski
Award Amount: $0.00

THE BBZDR RAT, NEW MODEL OF OBESITY/TYPE 2 DIABETES

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: HHS
Principal Investigator: Dennis L. Guberski
Award Amount: $452,092.00

New Rat Model of Autoimmune Diabetes And Arthritis

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Dennis L. Guberski
Award Amount: $171,353.00
Abstract:
DESCRIPTION (provided by applicant): The objectives of this proposal are to develop and characterize a new congenic rat model with spontaneous autoimmune disease. In Phase 1 we will establish a foundation colony of LEW.1WR1 rats and begin genetic crosses to introgress traits… More

Engineering Myoblasts for Transplantation

Award Year / Program / Phase: 2004 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF MASSACHUSETTS AMHERST
Principal Investigator: Edward H. Kislauskis
Award Amount: $223,141.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The primary goals of stem cell biology are to develop practical cell-based tools: 1) to enhance the repair of damaged organs and tissues; and 2) as vehicles for gene therapy to introduce engineered genes to the body to either correct a genetic defect or to… More

In-Stent Stenosis Model in Type 2 Diabetic Rats

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Tiangen Wu
Award Amount: $393,589.00
Abstract:
DESCRIPTION (provided by applicant): Coronary artery disease affects 12 million Americans and is the number on killer in the United States. Diabetes affects over 16 million Americans, with more than 80,000 new cases diagnosed each year. Cardiovascular complications of diabetes kills 75% of… More

Neurogenic Compounds for Treating Diabetic Complications

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Rebecca S. Tirabassi
Award Amount: $1,000,000.00
Abstract:
DESCRIPTION (provided by applicant): Neuronal dysfunction is the leading complication associated with diabetes. Diabetic patients experience both cognitive impairment and a collection of syndromes termed "diabetic neuropathies". Although many of the pathways involved in initiating… More

A Mucosal Vaccine for HSV-2

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Rebecca S. Tirabassi
Award Amount: $583,103.00
Abstract:
DESCRIPTION (provided by applicant): Approximately 1 out of every 5 Americans is infected with herpes simplex virus type 2 (HSV-2). Localized genital infection by HSV-2 results in painful recurring genital lesions while disseminated infection can involve multiple visceral organs and lethal… More

A Mucosal Vaccine for HSV-2

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: HHS
Principal Investigator: Kejian Yang
Award Amount: $2,563,533.00
Abstract:
DESCRIPTION (provided by applicant): Approximately 1 out of every 5 Americans is infected with herpes simplex virus type 2 (HSV-2). Localized genital infection by HSV-2 results in painful recurring genital lesions while disseminated infection can involve m ultiple visceral organs and lethal… More

New Rat Model For Autoimmune Therapy Safety/Efficacy

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Barbara Whalen
Award Amount: $594,141.00
Abstract:
DESCRIPTION (provided by applicant): Autoimmune diseases comprise the third most common category of illness in the United States affecting an estimated 22 million Americans. To date, therapeutic and preventive strategies for human autoimmune diseases (b ased on the restoration of immune… More

Developing small molecule therapeutics for lupus

Award Year / Program / Phase: 2011 / STTR / Phase I
Agency: HHS
Research Institution: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
Principal Investigator: Thomas R. Coleman – 508-459-7544
Award Amount: $583,195.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Systemic lupus erythematosus (SLE) affects ~ 2 million Americans with devastating impact on multiple organs, especially the skin, joints, kidney, and brain. Therapeutic strategies for lupus are largely palliative orimmunosuppressive with serious toxicities.… More

A Mucosal RSV Vaccine

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kejian Yang – 508-459-7544
Award Amount: $600,000.00
Abstract:
DESCRIPTION (provided by applicant): Human respiratory syncytial virus (RSV) is a highly infectious member of the paramyxovirus family causing upper and lower respiratory tract infections. RSV infection is the leading cause of pulmonary disease of the lower respiratory tract (bronchiolitis,… More

Developing Small MIF Inhibitors for Rheumatoid Arthritis

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Barbara Whalen – 508-459-7544
Award Amount: $452,431.00
Abstract:
DESCRIPTION (provided by applicant): Rheumatoid arthritis is a chronic inflammatory disorder that afflicts at least 2.5 million Americans. This autoimmune disease is 2-3 times more common in women and typically affects the small joints in the hands and feet. Current therapeutic strategies include… More