USA flag logo/image

An Official Website of the United States Government

HIGH SENSITIVITY, EASY TO USE, ENZYME IMMMUNOASSAY FOR PROGESTERONE IN SALIVA

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7957
Program Year/Program:
1988 / SBIR
Agency Tracking Number:
7957
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Biometallics Inc
Box 2251 Princeton, NJ 08543
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1988
Title: HIGH SENSITIVITY, EASY TO USE, ENZYME IMMMUNOASSAY FOR PROGESTERONE IN SALIVA
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE GOAL OF THIS RESEARCH AT BIOMETALLICS IS TO DEVELOP A RAPID, EASY TO USE ENZYMEIMMUNOASSAY, WITH ENHANCED SENSITIVITY FOR DETERMINING THE REPRODUCTIVE HORMONE, PROGESTERONE, IN SALIVA. THE MEASUREMENT OF PROGESTERONE INSALIVA IS ATTRACTIVE BECAUSE SAMPLING IS NONINVASIVE AND ESSENTIALLY STRESS FREE. BUT BECAUSE PROGESTERONE LEVELS INSALIVA ARE ONLY 1% OF PROGESTERONE LEVELS IN SERUM, ENHANCEDSENSITIVITY IS REQUIRED OVER CONVENTIONAL ENZYMEIMMUNOASSAY METHODOLOGY. A METHOD FOR INCREASING THE ENZYME SENSITIVITY OF HORSERADISH PEROXIDASE IS PRESENTED. THIS METHOD WILL BE DEMONSTRATED BY THE DEVELOPMENT OF AN ASSAY KIT FOR PROGESTERONE IN SALIVA. THIS ENHANCED SENSITIVITY METHOD WILL ALSO HAVE GENERAL APPLICATION TO THE DETERMINATION OF LOW LEVELS OF MANY OTHER HORMONES OR ANALYTES OF INTEREST.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Biometallics Inc
Box 2251 Princeton, NJ 08543

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No