USA flag logo/image

An Official Website of the United States Government

STABILIZATION OF PROTEINS BY CROSSLINKING

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
2338
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
2338
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SURMODICS, INC.
SURMODICS, INC. 9924 W 74TH ST EDEN PRAIRIE, MN 55344
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1986
Title: STABILIZATION OF PROTEINS BY CROSSLINKING
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $161,000.00
 

Abstract:

A PROJECT IS PROPOSED TO DEVELOP TECHNIQUES FOR STABILIZATION OF PROTEINS BY COVALENT CROSSLINKING. WE PLAN TO USE MONOCLONAL ANTIBODY SPECIFIC FOR T-2 TOXIN AS THE PRIMARY PROTEIN TO USE FOR DEVELOPING STABILIZATION TECHNOLOGY. USING LIGAND STABILIZATION TO DECREASE INACTIVATION DURING THE CROSSLINKING, WE PROPOSE TO EVALUATE THE EFFECTIVENESS OF INTRAMOLECULAR CROSSLINKING BETWEEN BOTH HYDROPHILIC AND HYDROPHOBIC GROUPS IN THE PROTEIN MOLECULES AS WELL AS INTERMOLECULAR CROSSLINKING WITH HIGHLY STRESS RESISTANT PROTEIN.

Principal Investigator:

Dr Melvin J Swanson
6129410080

Business Contact:

Small Business Information at Submission:

Bio-metric Systems Inc.
9932 W 74th St Eden Prairie, MN 55344

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No