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NOVEL SUPPORTS FOR CARBOHYDRATE IMMOBILIZATION

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
11100
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
11100
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SURMODICS, INC.
SURMODICS, INC. 9924 W 74TH ST EDEN PRAIRIE, MN 55344
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1991
Title: NOVEL SUPPORTS FOR CARBOHYDRATE IMMOBILIZATION
Agency: HHS
Contract: N/A
Award Amount: $359,363.00
 

Abstract:

THE IMMOBILIZATION OF BIOLOGICALLY ACTIVE MOLECULES ON SUPPORT MATRICES HAS MANY APPLICATIONS IN BIOTECHNOLOGY. PASSIVE ADSORPTION OF BIOMOLECULES (BOTH HYDROPHOBIC AND IONIC) TO POLYMERIC MATRICES IS THE LEAST COMPLICATED METHOD OF IMMOBILIZATION; HOWEVER, MANY BIOCHEMICALS DO NOT ADSORB WELL TO PLASTIC POLYMER SURFACES. IN PARTICULAR, CARBOHYDRATES ARE OFTEN DIFFICULT TO ADSORB WITH A SUFFICIENT DEGREE OF TENACITY. FACILE, COVALENT IMMOBILIZATION OF CARBOHYDRATE MOIETIES WOULD HAVE APPLICATION IN THE SURFACE MODIFICATION OF IMPLANTABLE DEVICES AND MAKE POSSIBLE THE DETECTION OF CARBOHYDRATE ANTIGENS IN ENZYME-LINKED IMMUNOSORBENT ASSAY PROCEDURES. BIO-METRIC SYSTEMS, INC., PLANS TO DEMONSTRATE PHOTOCHEMICALIMMOBILIZATION OF POLYSACCHARIDES TO INTRACTABLE POLYSTYRENESURFACES. THE TECHNOLOGY EXPECTED TO RESULT FROM THIS PROJECT WILL LEAD TO THE DEVELOPMENT OF DERIVATIZED SUPPORT MATERIALS FOR COVALENT LINKAGE OF MANY CARBOHYDRATES BY PROCEDURES THAT ARE LESS CUMBERSOME THAN OTHER COVALENT LINKAGE PROTOCOLS.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Bio-metric Systems Inc.
9924 W 74th St Eden Prairie, MN 55344

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No