Polysulfonate Immobilization for Thrombus Prevention

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 22315	Program Year/Program: 1993 / SBIR
Agency Tracking Number: 22315	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: SURMODICS, INC.
SURMODICS, INC. 9924 W 74TH ST EDEN PRAIRIE, MN 55344
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 1: Fiscal Year: 1993

Title: Polysulfonate Immobilization for Thrombus Prevention

Agency: HHS

Contract: N/A

Award Amount: $49,987.00

Abstract:
All synthetic materials which contact blood are thrombogenic and activate processes such as fibrin coagulation, platelet adhesion, and complement activation. Numerous investigations have been conducted to develop nonthrombogenic materials because of these observations. These include chemical modifications of the natural surface by the addition of hydrophilic moieties or immobilization of biologically active substrates. An alternative approach would be to incorporate anionic moieties into the polymer matrix, which is reported to result in a highly antithrombogenic surface. The goal of this Phase I research project is to utilize BSI's proprietary photoimmobiliz- ation technology to covalently immobilize photoreactive polyacrylamide-polysulfonate polymers onto various biomaterials. These polysulfonate coatings will potentially affect protein and platelet adhesion and lead to the development of long-lasting antithrombogenic surfaces.

Principal Investigator:
Peter H. Duquette
6128292700

Business Contact:

Small Business Information at Submission:

Bio-metric Systems, Inc.
9924 West 74th Street Eden Prairie, MN 55344

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No