MOLECULES PROBES FOR HUMAN B-LYMPHOTROPIC VIRUS

Award Information

Agency: Department of Health and Human Services

Branch: N/A

Contract: N/A

Agency Tracking Number: 11439

Amount: $45,000.00

Phase: Phase I

Program: SBIR

Solicitation Topic Code: N/A

Solicitation Number: N/A

Timeline

Solicitation Year: N/A

Award Year: 1989

Award Start Date (Proposal Award Date): N/A

Award End Date (Contract End Date): N/A

Small Business Information

Bio-molecular Technology, Inc.

Box 177

Middletown, MD 21769

United States

DUNS: N/A

HUBZone Owned: No

Woman Owned: No

Socially and Economically Disadvantaged: No

Principal Investigator

Phone: () -

Business Contact

Phone: () -

Research Institution

N/A

Abstract

THE HUMAN HERPES VIRUS TYPE 6 (HHV-6) IS A NOVEL HERPES VIRUS ISOLATED FROM FRESH HUMAN BLOOD MONONUCLEAR CELLS. ALTHOUGH NOT EXCLUSIVELY ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), HHV-6 MAY PLAY A ROLE IN LYMPHOPROLIFERATIVE ABNORMALITIES. AS A RECENT VIRUS ISOLATE, LITTLE IS KNOWN OF THE BIOLOGICAL PROPERTIES OF HHV-6, AND FEW REAGENTS ARE AVAILABLE TO INVESTIGATORS IN THE FIELD. THE DEVELOPMENT OF A BATTERY OF SUBGENOMIC DNA PROBES OF HHV-6 IS NECESSARY TO FACILITATE STUDIES AIMED AT ELUCIDATING THE ROLE OF THIS VIRUS IN HUMANS, INCLUDING ITS PUTATIVE PATHOLOGICAL ROLE. THE PHASE I EFFORT WILL CONCENTRATE ON DEVELOPING SUBGENOMICDNA PROBES OF HHV-6. DURING THE PHASE II EFFORT, THE BATTERY OF PROBES WILL BE EXPANDED AND FURTHER CHARACTERIZED, THE VIRAL GENOME WILL BE MAPPED, AND CLINICALDIAGNOSTIC KITS WILL BE DEVELOPED.

* Information listed above is at the time of submission. *

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MOLECULES PROBES FOR HUMAN B-LYMPHOTROPIC VIRUS