Many marine invertebrates produce some form of permanent cement or anchor system for stability in a hazardous environment. these attachment mechanisms must cope with constant fluxes in humidity, temperature, aeration, and salinity. it has long been suspected that if scientists could understand the… More

In recent years, it has become recognized that many of the problems experienced in initiating cell cultures in vitro with low seeding densities or newly isolated cells are substrate-related. specifically, studies have found that many of theseproblems stem from inadequate surface proper- ties found… More

Considerable effort has been focused on the use of cyanoa- crylates for clinical ocular repair as adjuncts to or in lieu of surgical procedures. through repeated studies, however, these adhesives have proved to be damaging to the eye tissue by causing inflammation, neovascularization and tissue… More

The common marine mussel, mytilus edulis, has evolved a mechanism for permanent attachment to many different surfaces underwater. the key to this animal's adhesive mechanism is a proteinaceous cement, i.e., mussel-adhesive protein (map), which recently has been sequenced. one specific aim of this… More

For over 30 years, a major goal of vascular surgery has been to improve bypass surgery through the development of an ideal prosthetic graft. although saphenous vein is the preferred substrate for occluded small-to-medium veins, frequently it is unavailable or unsuitable for a great number of… More