USA flag logo/image

An Official Website of the United States Government

CONSIDERABLE EFFORT HAS BEEN FOCUSED ON THE USE OF CYANOA- CRYLATES FOR…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4916
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4916
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Biopolymers Inc
309 Farmington Farmington, CT 06032
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: CONSIDERABLE EFFORT HAS BEEN FOCUSED ON THE USE OF CYANOA- CRYLATES FOR CLINICAL OCULAR REPAIR AS ADJUNCTS TO OR IN LIEU OF SURGICAL PROCEDURES.
Agency: HHS
Contract: N/A
Award Amount: $48,000.00
 

Abstract:

CONSIDERABLE EFFORT HAS BEEN FOCUSED ON THE USE OF CYANOA- CRYLATES FOR CLINICAL OCULAR REPAIR AS ADJUNCTS TO OR IN LIEU OF SURGICAL PROCEDURES. THROUGH REPEATED STUDIES, HOWEVER, THESE ADHESIVES HAVE PROVED TO BE DAMAGING TO THE EYE TISSUE BY CAUSING INFLAMMATION, NEOVASCULARIZATION AND TISSUE NECROSIS. AS AN ALTERNATIVE TO CYANOACRYLATES, THIS PROJECT PROPOSES THE USE OF MUSSEL-ADHESIVE PROTEIN (MAP) ASA TISSUE ADHESIVE IN OCULAR REPAIR. EXPERIMENTS WILL BE CONDUCTED WITH MAP ON RETINAL AND CORNEAL TISSUE IN VITRO AND IN SITU; MAP WILL ALSO BE EVALUATED FOR STRENGTH AND DURATION OF TISSUE BONDING. MAP IS A STRONG ADHESIVE CEMENTAND, UNLIKE CYANOACRYLATES, APPEARS TO BE BIOCOMPATIBLE; IT WILL LIKELY BECOME AN ATTRACTIVE ALTERNATIVE FOR THE TREATMENT OF OCULAR INJURIES.

Principal Investigator:

Paul t picciano
PRINCIPAL INVESTIGATOR
2036741444

Business Contact:

Small Business Information at Submission:

Bio-polymers Inc
309 Farmington Avenue Farmington, CT 06032

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No