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Company Information:

Company Name: Genaissance Pharmaceuticals
City: New Haven
State: CT
Zip+4: 06511
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (203) 773-1450

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,121,775.00 14
SBIR Phase II $3,071,333.00 5

Award List:

A STANDARD REPOSITORY FOR HUMAN GENE MAPPING

Award Year / Program / Phase: 1985 / SBIR / Phase I
Agency: HHS
Principal Investigator: Richard E Kouri
Award Amount: $50,000.00

A STANDARD REPOSITORY FOR HUMAN GENE MAPPING

Award Year / Program / Phase: 1989 / SBIR / Phase II
Agency: HHS
Principal Investigator: Richard E Kouri
Award Amount: $500,000.00
Abstract:
This project will establish a series of products to facilitate the generation of human genetic maps by preparingtransformed lymphocytes and extensive data profiles from members of oriental and caucasian families. the test panel will be of sufficient size so that researchers can: (1) detect even rare… More

PROBES TO DETECT EBV INTEGRATION IN HUMAN CELLS

Award Year / Program / Phase: 1989 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
This project will develop an assay to detect integrated forms of epstein-barr virus (ebv) dna in the genomes of cells transformed by this virus. the assay will utilize southern blotting and polymerase chain reaction methodology to identify the presence of virus-cell junction fragments indicative of… More

COUPLED AMPLIFICATION AND SEQUENCING OF DNA

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kouri, Richard E , Principal Investigator
Award Amount: $50,000.00

COUPLED AMPLIFICATION AND SEQUENCING OF DNA

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Kouri, Richard E , Principal Investigator
Award Amount: $499,033.00
Abstract:
The objective of this project is the commercialization of a method for the coupled amplification and sequencing ("cas") of dna. kits will be produced that enable the simultaneous sequencing of both strands of multiple dna fragments using as little as 20 femtomoles template. cas is based on a… More

Resources for Genome wide Selection and Mapping of Genes

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gualberto Ruano
Award Amount: $78,036.00
Abstract:
This project will develop methodology for high-throughout identification of cDNAs from largesegments of genomic DNA cloned into yeast artificial chromosomes (YACs) and from amplified genomicDNA corresponding to a desired micro-dissected chromosome band. We will use cDNA libraries fromhuman spleen,… More

Standard Reagents for Analyzing Human Genetic Diversity

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gualberto Ruano
Award Amount: $78,036.00
Abstract:
A considerable number of DNBA restriction fragment length polymorphism (RFLPs) have beendiscovered and genotyped in populations and in reference families. RFPL's result from single base-pairdifferences within restriction enzyme recognition sequences which lead to fragments of variable… More

DNA Amplification from Microdissected Chromosomes

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Clark Huckaby
Award Amount: $78,915.00

Large Throughput Multiplex Analysis of Gene Expression

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gualberto Ruano
Award Amount: $100,000.00
Abstract:
We will develop resources for large-throughput analysis of gene expression. The complement of genesexpressed in a given cell varies during development, in disease states and in response to hormonal sgene expression are the basis of cancer. This project will show the feasibility of "Multiplex… More

Novel Repeat Elements for Genome Analysis

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Wan-Liang Li
Award Amount: $96,792.00
Abstract:
The goal of this Phase I project is to isolate and characterize new chromosome-specific human repetelements. The resulting probes will be valuable for cytogenetic cancer diagnostics. Our preliminaryrandom amplification of polymorphic DNA (RAPD) is a valuable approach for the discovery of… More

N/A

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $100,000.00

Standard Reagents for Molecular Haplotyping of Humans

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: NSF
Principal Investigator: Gualberto Ruano
Award Amount: $65,000.00

DNA Amplification from Microdissected Chromosomes

Award Year / Program / Phase: 1996 / SBIR / Phase II
Agency: HHS
Principal Investigator: Clark Huckaby
Award Amount: $750,000.00
Abstract:
We will develop kits, services, and reagents useful in the processes of generating and employingamplified DNA mini-libraries (i.e., amplified products) from microdissected human chromosomefragments. The focus of Phase I studies will be development of standard protocols for generating… More

DELETION FACTORIES FOR GENOMIC ANALYSIS OF 100 KB CLONES

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $100,000.00

Directed Multiplex DNA Sequencing by Hybridization

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: DOE
Principal Investigator: Dr. Gualberto Ruano , Scientific Director
Award Amount: $75,000.00

Directed Multiplex DNA Sequencing by Hybridization

Award Year / Program / Phase: 1997 / SBIR / Phase II
Agency: DOE
Principal Investigator: Dr. Gualberto Ruano , Scientific Director
Award Amount: $750,000.00
Abstract:
41186 BIOS Laboratories, Inc. The ultimate goal of the Human Genome program is to obtain the entire sequence of the genetic makeup of the human body. This research has mostly encompassed large scale DNA sequencing projects, with interdisciplinary teams of biochemists, engineers, and computer… More

GENE DISCOVERY BY FUNCTIONAL PROBING OF GENOME LIBRARIES

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ruano, gualberto
Award Amount: $100,000.00

SITE SPECIFIC CLONING OF GENOMIC DNA IN VIVO

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bentley, kevin l
Award Amount: $99,996.00

DELETION FACTORIES FOR GENOMIC ANALYSIS OF 100 KB CLONES

Award Year / Program / Phase: 1997 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $572,300.00