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DEVELOPMENT OF AN ELISA TEST FOR ANTIBODIES TO HUMAN B-LYMPHOTROPHIC VIRUS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7102
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7102
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SERACARE LIFE SCIENCES, INC.
SERACARE LIFE SCIENCES, INC. 1935 AVENIDA DEL ORO, STE F OCEANSIDE, MD 92056 0582
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: DEVELOPMENT OF AN ELISA TEST FOR ANTIBODIES TO HUMAN B-LYMPHOTROPHIC VIRUS
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

NIH RESEARCHERS HAVE RECENTLY ANNOUNCED THE ISOLATION OF A HUMAN B-LYMPHOTROPIC VIRUS (HBLV) FROM SIX INDIVIDUALS WITH VARIOUS LYMPHOPROLIFERATIVE AND IMMUNE DISORDERS. HBLV APPEARS TO BELONG TO THE GROUP OF HUMAN HERPES VIRUSES AND MAY BE ASSOCIATED WITH B LYMPHOPROLIFERATIVE DISORDERS. EARLY SEROLOGICAL TESTS USING INDIRECT IMMUNOFLUORESCENCE METHODS REVEALED THAT ONLY 4 OF 220 RANDOM, HEALTHY BLOOD DONORS WERE SEROPOSITIVE FOR HBLV ANTIBODIES. MORE RECENT REPORTS STATE THAT THE PREVALENCE OF HBLV INFECTION MAY BE HIGHER. AN ELISA-BASED ASSAY FOR HBLV ANTIBODY DETECTION WOULD FACILITATE FURTHER STUDY OF THE PREVALENCE OF INFECTION WITH THIS VIRUS AND THE RELATION OF INFECTION TO HUMAN DISEASE. HBLV HAS BEEN SEEN TO BE INFECTIOUS IN SEVERAL CELL LINES ASWELL AS IN FRESH B LYMPHOCYTES. IN THIS PROPOSAL, BIOTECH RESEARCH LABORATORIES, INC. PRESENTS ITS PLAN FOR USING HBLVCULTURED IN THE HSB-2 CELL LINE TO DEMONSTRATE THE FEASIBILITY OF DEVELOPING AN ELISA-BASED TEST KIT FOR HBLV ANTIBODY DETECTION.

Principal Investigator:

Anne j bodner phd
3012510800

Business Contact:

Small Business Information at Submission:

Biotech Research Laboratories
1600 East Gude Drive Rockville, MD 20850

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No