Biotech has developed a system for labeling dna fragments with hapten-modified ""tails'' which can be detected by immunological methods using enzyme-conjugated antibodies. the detection sensitivity of this system is 274 picogram, which is sufficient to detect single copy genes in human dna. the aim… More

The overall objective of this program is to develop cost-effective technology for the scale-up of mammalian cell culture for the manufacture of products such as monoclonal antibodies or genetically engineered proteins. the approach involves growth of cells in the interstices of a porous matrix,… More

Prevalence studies for hiv-1 infection in newborns are difficult to obtain because the commonly used antibody assays are not appropriate for testing babies. babies carrythe maternal antibody for up to 12 to 18 months after birth,so all babies born to seropositive mothers will also test positive. yet… More

A simple, inexpensive and reliable format amendable for testing large numbers of clinical samplesfor the presence of HCV RNA will be developed in the course of this contract. The conditions for samplecollection, storage and processing will be carefully controlled to ensure maximum reproducibility… More

A novel, unique, rapid and reliable multiplex RT-PCR test will be developed for the simultaneous deviral pathogens, HTLV- I/II, HIV-1, HBV and HCV, frequently associated with transfusion- transmittedtranscription of HCV RNA, and amplification of HTLV-I/ II, HIV-1 and HBV DNAs will be carried out… More