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Hot Flash Research Tool for Broad Population Research Studies

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
76021
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
EB006013
Solicitation Year:
N/A
Solicitation Topic Code:
NIBIB
Solicitation Number:
N/A
Small Business Information
Advanced Medical Electronics Corp.
6901 East Fish Lake Road Suite #190 Maple Grove, MN 55369-5457
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2010
Title: Hot Flash Research Tool for Broad Population Research Studies
Agency: HHS
Contract: 2R44EB006013-02A2
Award Amount: $754,728.00
 

Abstract:

DESCRIPTION (provided by applicant): This work is focused on exploring the physiological processes and therapies associated with hot flashes. The project proposes to develop a tool for use by researchers studying hot flashes in broad population research st udies. Hot flashes are experienced by approximately 80 percent of American women between the ages of 45 and 54 and are a significant concern during menopause. Typically expressed as a period of intense heat with sweating, flushing and rapid heartbeat, epis odes usually last from five to ten minutes, but have been reported to last as long as an hour. These events frequently occur at night, and may be repeated anywhere from a few times per week to dozens of times per day. No longer relegated simply to women re aching the end of their child bearing years, hot flashes now affect breast cancer survivors, women with chemotherapy-induced ovarian failure, oopherectomized women, women being treated for endometriosis or infertility with gonadotropin- releasing hormone ( GnRH) agonists such as Lupron, and men with prostate cancer undergoing androgen deprivation therapy (ADT). Hot flashes are often disruptive and unpleasant, with broad overall health consequences affecting work responsibilities, social activities, sleep, et c. The fundamental physiological triggering mechanisms of hot flashes are not well understood although hot flash therapies are an area of active research often including large therapy trials in broad populations. These studies require an objective measure of the hot flash phenomenon that optimally correlates with self-reported diary data, is specific to hot flashes, and is accurate under ambulatory conditions. PUBLIC HEALTH RELEVANCE: The proposed project develops technology for researchers studying hot flashes in men and women.

Principal Investigator:

Gary D. Havey
7634634814
GHAVEY@AME-CORP.COM

Business Contact:

Tom Hendrickson
thendrickson@ame-corp.com
Small Business Information at Submission:

ADVANCED MEDICAL ELECTRONICS CORPORATION
ADVANCED MEDICAL ELECTRONICS CORPORATION 6901 E FISH LAKE RD, STE 190 MAPLE GROVE, MN -

EIN/Tax ID: 141169382
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No