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THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF IMPROVED…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4690
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4690
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
BOSTON BIOTECHNOLOGY CORPORATION
BOSTON BIOTECHNOLOGY CORPORATION 64 GROVE STREET WATERTOWN, MA 02472
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF IMPROVED NONISOTOPIC HOMOGENEOUS IMMUNOASSAYS.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF IMPROVED NONISOTOPIC HOMOGENEOUS IMMUNOASSAYS. INITIALLY, A METHOD WILL BE DEVELOPED WHEREBY SULFHYDRL GROUPS WILL BE TRANSFERRED FROM AN ANTIGEN TO AN ANTIBODY SELECTIVELY NEAR THE LATTER'S ANTIGEN BINDING SITE. VARIOUSFLUORESCENCE OR ENZYME PROBES CAN THEN BE ATTACHED TO THE ANTIBODY AT THESE SITES. IN VIEW OF THE PROXIMITY OF ANTIGENS TO THE ANTIGEN BINDING SITE, THESE PROBES ARE EXPECTED TO RESPOND DIRECTLY TO ANTIGEN BINDING. ANTIBODIESSO LABELED ARE THEREFORE IDEAL FOR HOMOGENEOUS IMMUNOASSAYS IN WHICH THE ADDITION OF A TEST SAMPLE CONTAINING THE ANTIGENIC ANALYTE WILL ELICIT AN IMMEDIATE MEASURABLE RESPONSE, SUCH AS CHANGES IN FLUORESCENCE INTENSITY OR ENZYME ACTIVITY. SUCH IMMUNOASSAYS POSSESS IMPROVEMENTS OVER EXISTING ASSAY PROCEDURES WITH RESPECT TO SENSITIVITY AS WELL AS REDUCTIONS IN COST, TIME, AND LABOR. IMMUNOASSAYS ARE ALREADY USED EXTENSIVELY FOR DIAGNOSTIC TESTS IN MEDICINE. YET UNTAPPED ARE MARKETS IN AGRICULTURE,ENVIRONMENTAL PROTECTION, PHARMACEUTICALS, AND OTHER INDUSTRIES THAT REQUIRE MICROANALYSES OF CHEMICAL SUBSTANCES.

Principal Investigator:

Terence tao
PRINCIPAL INVESTIGATOR
6177422010

Business Contact:

Small Business Information at Submission:

Boston Biotechnology Corp
20 Staniford Street Boston, MA 02114

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No