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ACCELERATED WOUND HEALING WITH FIBROBLAST GROWTH FACTOR

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4931
Program Year/Program:
1988 / SBIR
Agency Tracking Number:
4931
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
California Biotechnology, Inc.
2450 Bayshore Parkway Mountain View, CA 94043
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1988
Title: ACCELERATED WOUND HEALING WITH FIBROBLAST GROWTH FACTOR
Agency: HHS
Contract: N/A
Award Amount: $500,000.00
 

Abstract:

BASIC AND ACIDIC FIBROBLAST GROWTH FACTORS (FGF) ARE TWO PRIMARY MITOGENS FOR CAPILLARY ENDOTHELIAL CELLS. BOVINE BASIC FGF, ISOLATED FROM PITUITARIES, WILL BE USED IN RAT WOUND HEALING MODELS TO DETERMINE WHETHER THIS FACTOR CAN ACCELERATE THE RATE OF WOUND HEALING THROUGH PROMOTING ANGIOGENESIS. THIS IS THE FIRST STEP TOWARDS DEVELOPING A THERAPY THAT WILL BE USED IN THE TREATMENT OF BURN AND OTHERTRAUMA VICTIMS WHO HAVE POORLY HEALING WOUNDS. TO OBTAIN A SOURCE OF THE HUMAN FGFS, FOR FURTHER ANIMAL TESTS AND FOR EVENTUAL CLINICAL TRIALS, THE DNA SEQUENCES ENCODING BOTH BASIC AND ACIDIC FGF WILL BE CLONED. THIS WILL ALLOW THE FUTURE DEVELOPMENT OF RECOMBINANT DNA EXPRESSION SYSTEMS FORHUMAN PROTEINS.

Principal Investigator:

John C Fiddes
Principal Investigator
4159661550

Business Contact:

Small Business Information at Submission:

California Biotechnology Inc.
2450 Bayshore Frontage Rd Mountain View, CA 94043

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No