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High-Efficiency Tunable Fluorescence Emission Filter

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
25209
Program Year/Program:
1996 / SBIR
Agency Tracking Number:
25209
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
CAMBRIDGE RESEARCH AND INSTRUMENTATION
CAMBRIDGE RESEARCH AND INSTRUMENTATION, INC. WOBURN, MA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1996
Title: High-Efficiency Tunable Fluorescence Emission Filter
Agency: HHS
Contract: 1 R43 MH53690-1,
Award Amount: $686,507.00
 

Abstract:

Tunable filters developed by us, based on electrically-tuned liquid crystal waveplates, providefluorescence microscopists with fast, continuous and automated selection of emission wavelengthwithout vibration, image shift, or detectable degradation of image quality. They can be used to convertany high-resolution monochromatic camera into a multispectral camera. On the other hand, these liquidcrystal tunable filters (LCTF's) presently offer rather low throughput (10 to 25%) which limits theirusefulness in photon-limited fluorescence applications. Our aim is to determine the feasibility ofdeveloping a new type of liquid crystal tunable filter with efficiency of 70% or more. Improvements inefficiency will accrue mainly from: 1) use of a novel optical configuration that filters all input polarizationstates instead of just one linear polarization state; and 2) improving the efficiency of our liquid crystaltunable waveplates.

Principal Investigator:

Clifford Hoyt
6174912627

Business Contact:

Small Business Information at Submission:

Cambridge Research
21 Erie Street Cambridge, MA 02139

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No