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MASS SPECTROMETRIC SURFACE ANALYSIS OF MEMBRANES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19267
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
19267
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Charles Evans & Associates
301 Chesapeake Drive Redwood City, CA 94063
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: MASS SPECTROMETRIC SURFACE ANALYSIS OF MEMBRANES
Agency: HHS
Contract: N/A
Award Amount: $49,936.00
 

Abstract:

THE PHASE I RESEARCH WILL EVALUATE THE FEASIBILITY OF USING TIME-OF-FLIGHT SECONDARY ION MASS SPECTROMETRY (TOF-SIMS) TO PROVIDE SENSITIVE AND STRUCTURALLY SIGNIFICANT CHARACTERIZATIN OF THE SURFACE COMPOSITION OF BIOLOGICAL MEMBRANES. THE RESEARCH WILL ANALYZE A VARIETY OF MODEL MEMBRANE SYSTEMS IN ORDER TO FULLY EVALUATE THIS FEASIBILITY. THE DATA PRODUCED IN THIS STUDY WILL BE EVALUATED SPECIFICALLY WITH REGARD TO ITS DIAGNOSTIC VALUE IN ELUCIDATION MEMBRANE CHEMICAL STRUCTURE. THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO DEVELOP ROUTINE, QUANTITATIVE SURFACE ANALYSIS TECHNIQUES FOR THE CHEMICAL ANALYSIS OF MEMBRANE SURFACES. THE ACHIEVEMENT OF THIS OBJECTIVE COULD FIND EXTENSIVE APPLICATION IN A VARIETY OF BIOLOGICAL SCIENCES INCLUDING SYNTHETIC MEMBRANE DEVELOPMENT, FUNDAMENTAL INVESTIGATIONS OF MEMBRANE STRUCTURE/FUNCTION RELATIONSHIPS AND POSSIBLY, BETTER UNDERSTANDING OF THE ROLE BIOMEMBRANES PLAY IN THE STATE OF HEALTH OF ORGANISMS.

Principal Investigator:

Constance M John
4153694567

Business Contact:

Small Business Information at Submission:

Charles Evans And Associates
301 Chesapeake Drive Redwood City, CA 94063

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No