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The MOST-Monitor for Oxygenation of Surface and Tissue

Award Information

Department of Defense
Award ID:
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Cybernet Systems Corporation
3885 Research Park Drive Ann Arbor, MI 48108-2247
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 1995
Title: The MOST-Monitor for Oxygenation of Surface and Tissue
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $69,102.00


Transmittance pulse oximetry is currently the preferred method of noninvasive oxgenative monitoring. However, this type of monitoring is limited with regards to peripheral probe placement, creating an inability to measure deep-tissue oxygenation to the level desired. Recently reflective methods have been applied to pulse oimetry; however, the reflected signal isdifficult to measure and interpret. The reflective studies performed to date utilize individual probe placement and measurements schemes. We propose an alternative approach invoking multiple probes fabricated to incorporate deep tissue oxygenation characterization in conjunction with surface assessment. A volumetric profile will be established to formulate a more complete representation of systemic oxygenation - a profile with increased resolution and sensitivity. Associated experimental data integrated with theoretical analysis will assist in the formulation of a coherent mathematical model. Time resolved spectroscopy will be investigated using pulse sequencing as opposed to individual narrow pulses. This approach will augment experimental tissue diffusion investigation. The Phase I study will produce the sensor system design to best detect surface and deep tissue oxygenation noninvasively.

Principal Investigator:

Jennifer L. Griffin

Business Contact:

Small Business Information at Submission:

Cybernet Systems Corp
1919 Green Road Suite B 101 Ann Arbor, MI 48105

EIN/Tax ID: 430924383
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No