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Company Information:

Company Name: Chesapeake Perl, Inc.
City: SAVAGE
State: MD
Zip+4: 20763-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (301) 317-9300

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $397,738.00 5
SBIR Phase II $2,815,415.00 3

Award List:

Colorimetric End-of-Service Life Indicator for Mask Filters

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency / Branch: DOD / CBD
Principal Investigator: Terry Chase, President
Award Amount: $69,922.00
Abstract:
This proposal develops the basis for a self-tuning expression system exploitingfluorescing insect larvae. Chesapeake PERL, Inc., co-founded by Drs. Bentley andPham, was formed to exploit insects as host organisms, where the eventual biomanufacturingprocess is comprised of parallel self-regulating

Mass Customization Biomanufacturing Process

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency / Branch: DOD / CBD
Principal Investigator: Nikolai Beek, Chief Scientific Officer
Award Amount: $0.00
Abstract:
"Chesapeake PERL, Inc aims to develop baculovirus-based expression in insect larvae from bench-scale to mass manufacturing. The technology platform consists of automated mass insect rearing, and inoculation combined with monitoring of protein expressionlevels in larvae via a fluorescent reporter. … More

Mass Customization Biomanufacturing Process

Award Year / Program / Phase: 2002 / SBIR / Phase II
Agency / Branch: DOD / CBD
Principal Investigator: Nikolai Beek, Chief Scientific Officer
Award Amount: $727,950.00
Abstract:
"Chesapeake PERL, Inc aims to develop baculovirus-based expression in insect larvae from bench-scale to mass manufacturing. The technology platform consists of automated mass insect rearing, and inoculation combined with monitoring of protein expressionlevels in larvae via a fluorescent reporter. … More

Improved Protein Manufacturing in Insect Expression Systems

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency / Branch: DOD / CBD
Principal Investigator: Terry Chase, President & CEO
Award Amount: $69,995.00
Abstract:
Chesapeake PERL is a contract manufacturing company using the baculovirus expression system for mass production of proteins in lepidopterous insect larvae. PERL's automated in-line insect mass rearing and inoculation systems enables the production oflarge quantities of complex, biologically fully… More

Improved Protein Manufacturing in Insect Expression Systems

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Nikolai van Beek, CSO
Award Amount: $1,343,270.00
Abstract:
The central theme of the proposed research is improvement of the quality of product proteins manufactured in insect larvae. The approach is twofold: create the most favorable conditions for the expressed protein to mature, and create the least favorable conditions for proteolytic breakdown in the… More

Alternative Feedstocks, Pretreatment/Biochemical

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: DOE
Principal Investigator: George W. Buchman, Dr.
Award Amount: $99,906.00
Abstract:
Cellulose is a highly sustainable global resource with considerable relevance to bio-ethanol production. Lignocellulose is a naturally occurring complex of plant-derived materials that includes the hydrophilic sugar polymers cellulose and hemicellulose, and the hydrophobic organic polymer lignin.… More

Alternative Feedstocks, Pretreatment/Biochemical

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: DOE
Principal Investigator: George W. Buchman, Dr.
Award Amount: $744,195.00
Abstract:
Cost effective enzymatic lignin degradation could play a key role in enabling commercially viable processes for producing fuel ethanol from woody feedstocks, such as corn stover, switchgrass, hybrid poplar, willow, loblolly pine, and eucalyptus. This project focuses on the identification,… More

Production and Evaluation of a Vault-CCL21 Nanocapsule as a Lung Cancer Treatment

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: George Buchman – 301-317-9300
Award Amount: $157,915.00
Abstract:
DESCRIPTION (provided by applicant): Project Summary: Lung cancer is the leading cause of cancer death in the United States and is responsible for more deaths each year than breast, prostate, colon, hepatic, renal and skin cancers combined. Viewed in economic terms, in the United States, the value… More