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Preparation of Vaginal Lactobacillus Suppository

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
24777
Program Year/Program:
1996 / SBIR
Agency Tracking Number:
24777
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Chrisope Technologies, Inc.
3941 Ryan Street Lake Charles, LA 70605
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1996
Title: Preparation of Vaginal Lactobacillus Suppository
Agency: HHS
Contract: 1 R43 AI36021-1,
Award Amount: $742,790.00
 

Abstract:

We will develop a commercially available vaginal suppository containing a hydrogenperoxide-producing strain of Lactobacillus for use in colonization of the vagina. In this project, a strainof Lactobacillus will be identified based on adherence to vaginal epithelial cells, hydrogen peroxideproduction, and growth characteristics. Methods for strain preservation and maintenance of viability,biochemical, physiologic and genetic characteristics during large scale production will be optimized. Theeffect of suppository delivery formats and components including various cream and gel bases, growthor nutritional additives on successful bacterial rejuvenation, adherence and hydrogen peroxide productionwill be investigated.

Principal Investigator:

Gerald Chrisope
3184791000

Business Contact:

Small Business Information at Submission:

Chrisope Technologies, Inc.
3941 Ryan Street Lake Charles, LA 70605

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No