To address the Army's need for a non-invasive, rapid, field-deployable and inexpensive hydration status monitoring technology, ChromoLogic proposes to develop a new Ocular Hydration Monitor (OCHYMO). OCHYMO is based on measuring the plasma omolality by non-invasively measuring the osmolality of the… More

In order to address its urgent need to track and identify critical material, the Army is in need of a DNA based barcoding system that would enable unforgible, unambiguous and easily readable system for labeling and tracking military material. To meet this need, ChromoLogic proposes to develop a new… More

To address the Army's need for a non-invasive, rapid, field-deployable and inexpensive hydration status monitoring technology, in Phase I, ChromoLogic LLC (CL) developed and demonstrated a new Ocular Hydration Monitor (OCHYMO) system. OCHYMO is based on measuring the plasma omolality by… More

In order to address the Army's need for a handheld device capable of locating any foreign body as well as differentiate between viable and non-viable tissue, ChromoLogic LLC (CL) proposes to develop a Debridement And Vitality Assessment by Near Infrared Spectroscopy (DAVANIS) system. The… More

To address the Army's urgent need for a DNA based barcoding system that would enable unforgeable, unambiguous and easily readable system for labeling and tracking military material, in Phase I, ChromoLogic LLC (CL) has developed and demonstrated a new reagent-free DNA based barcode and reader (RDB)… More

To address the Air Force need for an environmental boundary to shield aircraft surfaces from environmental contaminates during in-field repair, ChromoLogic proposes to develop a new secure anchoring environmental boundary (OCTOPUS) as an environmental boundary that protects composite aircraft… More

The DOE is interested in new instrumentation that can be used to reveal the function roles in biofilms with depth and to identify non-cellular biofilm constituents. Current instrumentation techniques are often destructive and/or prohibitively expensive, and no instruments are capable of real-time… More

To address NASA's need for a method to preserve blood and urine samples from astronauts collected during flight, Chromologic (CL) proposes to develop a novel Fluid Preservation System (FPS). FPS is based on collecting and sealing fluids in a sterile, hermetically sealed volume, with automatic… More

To address the Armyf?Ts need for a hand-held device to assist surgeons in locating all types of foreign bodies (FBf?Ts) and devitalized tissue during wound debridement procedures, in Phase I, ChromoLogic LLC (CL) has developed and demonstrated a new Debridement And Vitality Assessment by Near… More

In order to address the Navy's need for a diagnostic chest seal to autonomously alert care providers of the onset of tPTX/hPTX, ChromoLogic LLC (CL) proposes to develop a Pressure-Reactive Chest Seal (ReSeal) that is based on adapting a liquid manometer into a compact, microfabricated structure that… More

To address NASA's need for a method to preserve human biological samples, mostly blood and urine, from astronauts collected during flight under ambient conditions, ChromoLogic (CL) has developed a novel Fluid Preservation System (FPS). FPS is based on collecting and sealing fluids in a sterile,… More

Accurately detecting early cancer biomarkers can dramatically improve cancer treatment and prevention. Non-coding RNAs (ncRNAs) have recently shown promise as cancer-related biomarkers that could be used in early detection and treatment of cancer. However,current methods for detection of ncRNAs are… More

The Department of Energy (DOE) is interested in innovative research involving fiber-optic radiation detectors and associated signal processing electronics for the identification of specific radioisotopes. Specifically, the DOE is keenly interested in new fiber-optic instrumentation to be used to… More

To address NASA's need for alternative methods for ambient preservation of human biological samples collected during extended spaceflight and planetary operations, Chromologic (CL) proposes to develop a novel Biological Sample Ambient Preservation (BioSAP) device. BioSAP device is based on an… More

Human plasma offers the promise of a revolution in biomarker-based disease diagnosis and therapeutic monitoring. Absence of a trained phlebotomist in remote locations limits the diagnostic potential of the human proteome, as current self-administered point-of-care extraction volumes are insufficient… More

To address the Office of the Secretary of Defense, Defense Health Program"s (OSD/DHP) need for an innovative concept for effective, objective diagnosis of subjective tinnitus in military personnel, ChromoLogic (CL) proposes to develop the OPical TINnitus Assessment or (OPTINAS) system based on… More

To address the Army"s need for an innovative concept for non-invasive, compact, robust monitoring system to monitor the oxidative status of military personnel, ChromoLogic (CL) proposes to develop the OCular Oxidative Stress Monitor (OCOSMO) technology based on non-invasive optical measurements… More

The Army seeks a novel and practical approach for the collection and long-term preservation of RNA and other nucleic acids (e.g., microRNA, DNA) from blood products at near room temperature conditions. To address this unmet need, ChromoLogic, LLC, (CL) proposes to develop an Integrated Membrane for… More

The parasite Plasmodium vivax, transmitted by the Anopheles mosquito, is the second major cause of malaria worldwide and the major cause of malaria outside Africa. The infection is characterized by a chronic course of malaria with acute episodes of relapse after months to years of asymptomatic… More

DESCRIPTION (provided by applicant): Although there are ~300,000 to 600,000 individuals in the United States with active uveitis, there is no clinically accepted method for quantitative assessment of ocular flare that would result in rapid, non-invasive diagnosis of uveitis. Current methods of… More