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Integrated Protein/Nucleic Acid Microarray CB Detector

Award Information

Agency:
Department of Defense 		Branch:
Defense Threat Reduction Agency 		Award ID:
63560 		Program Year/Program:
2003 / SBIR
Agency Tracking Number:
T031-0146 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
CIENCIA, INC.
111 ROBERTS ST, STE K EAST HARTFORD, CT 06108-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2003
Title: Integrated Protein/Nucleic Acid Microarray CB Detector
Agency / Branch: DOD / DTRA
Contract: DTRA01-03-P-0191
Award Amount: $100,000.00
 

Abstract:

The objective of the proposed program is to develop a portable, low-cost, label-free (reagentless), microarray system capable of near real-time simultaneous detection and identification of multiple analytes (bacteria, viruses, spores, toxins) with highsensitivity and low false alarm rate. Notably, the system will be capable of detection/identification of agents on the basis of protein and/or nucleic acid recognition. The system will consist of a disposable biosensor chip and an optical reader devicewith an integrated sample collector. Detection is based on a proprietary optical transduction technology known as grating-coupled surface plasmon resonance imaging. In the Phase I effort we will demonstrate the operation of the collector anddetection/identification components and perform a preliminary specification and design of a system to be built and tested in a Phase II effort. The proposed technology is dual use. Potential applications include hospitals, where nosocomial infections mayarise; large buildings where accidental contamination with mold spores, Legionella and other pathogens may create health hazards; recreational water and drinking water supplies where waterborne pathogens are a great concern, and the food industry, wherethere is a need for sensitive methods for on-line and real-time detection of pathogens.

Principal Investigator:

Salvador M. Fernandez
President
8605289737
fernandez@ciencia.com

Business Contact:

Arturo O. Pilar
Vice President
8605289737
apilar@ciencia.com
Small Business Information at Submission:

CIENCIA, INC.
111 Roberts Street, Suite K East Hartford, CT 06108

EIN/Tax ID: 631009790
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No