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Toxicity Evaluation Module

Award Information

Department of Defense
Air Force
Award ID:
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
CogniTech Corporation
1060 East 100 South Suite 306 Salt Lake City, UT 84102-1683
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2001
Title: Toxicity Evaluation Module
Agency / Branch: DOD / USAF
Contract: F33615-01-M-6032
Award Amount: $100,000.00


Many chemicals have limited occupational health and toxicological data. A computerized fuzzy logic expert system module could synthesize information from diverse sources and support the assessment of a chemical's toxicity endpoints and associateduncertainty. The interdisciplinary team of toxicologists, chemists, and computer scientists will develop a fuzzy logic methodology and knowledge base for determining toxicity endpoints. The investigators will use this methodology to develop a prototypeweb-based fuzzy logic expert system, integrated with an interactive user interface and database. The investigators will create the knowledge base rules and facts from QSAR-related variables (i.e., chemical physical properties) and existing toxicologicaldata. This software will be evaluated and demonstrated with the adrenocortical endocrine disruption toxicity endpoint. Phase II will extend Phase I's methodology and technologies to develop a fully functional software prototype that will estimate healthhazards over a larger spectrum of toxicity endpoints relevant to the Air Force.The toxicology decision support module will have applications as an initial screening mechanism for industrial chemical manufacturers and their customers. An additional marketis as an educational tool for universities, hospitals, and emergency response agencies.

Principal Investigator:

Wendell Duncan
Senior Software Engineer

Business Contact:

Jerome Soller
Small Business Information at Submission:

1060 East 100 South, Suite 202 Salt Lake City, UT 84102

EIN/Tax ID: 870562064
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No