Single Cell Micro-chamber Array analysis
DESCRIPTION (provided by applicant): Abnormalities in the cytosol of subpopulations of cells are often a hallmark of pathology. Most analysis methods will only provide information on the cytosol of cell populations as a whole, not for individual cells or s
ubpopulations of cells. To overcome this, we propose to develop Single Cell Micro-chamber Array (SiCMA) technology. This approach is based on preliminary studies in the laboratory of Dr. Kuypers at CHORI to use microchamber arrays to report on the stochast
ic distribution of cytosolic components. In this Phase I SBIR we aim to prove the principle of this approach and set the stage for further development in a joint effort between EandM devices and CHORI. The successful completion of the proposed studies will
establish our ability to measure cytosolic components correlated with cell surface markers in a complex cell population, and provide the basis for commercialization of this technology.
Small Business Information at Submission:
Principal Investigator:Eri Takahashi
EANDM DEVICES, INC.
EANDM DEVICES, INC. 2973 Santos Lane # 301 Walnut Creek, CA 94597
Number of Employees: