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AUTIMICROBIAL IMPREGNATION OF SILICONE RUBBER

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
1517
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
1517
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Colorado Biomedical Inc.
6851 Highway 73 Evergreen, CO 80439
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1986
Title: AUTIMICROBIAL IMPREGNATION OF SILICONE RUBBER
Agency: HHS
Contract: N/A
Award Amount: $440,000.00
 

Abstract:

SILICONE RUBBER AND OTHER ARTIFICIAL MATERIALS WHICH CONTACT BODY TISSUES SOMETIMES IRRIRATE THE TISSUES CAUSING UNWANTED REACTION IN THE BODY. IN SBIR PHASE I, TREATMENTS WHICH MINIMIZE THESE EFFECTS WILL BE GIVEN PRELIMINARY SCREENING. THE TREATMENTS INCLUDE CHEMICAL PROCEDURES FOR PROTECTING THE SURFACE OF THE POLYMERIC MATERIALS AGAINST TISSUES ENCAPSULATION, CHANGES IN LOCAL VASCULARITY, INFECTIONS, AND THROMBOGENICITY. IN VITRO TESTS, AS WELL AS ANIMAL TESTS (PRIMARILY RATS), WILL BE CONDUCTED, COMPARING THE UNTREATED AND THE TREATED MATERIALS. IT IS EXPECTED THAT THE MATERIALS THAT HAVE BEEN TREATED WILL BE BETTER ACCEPTED BY THE ANIMAL MODEL TISSUES THAN WOULD BE THE SAME MATERIALS UNTREATED. IN PHASE II, THE RESULTS OF PHASE I WILL BE EXTENDED AND QUANTIFIED, LEADING TO CLINICAL EXPERIMENTS IN WHICH THE MOST PROMISING OF THE TREATMENTS THAT WERE DEVELOPED IN PHASE I WILL BE EVALUATED FOR APPLICATIONS IN HUMANS.

Principal Investigator:

J.b. Newkirk
0

Business Contact:

Small Business Information at Submission:

Colorado Biomedical Inc.
6851 Highway 73 Evergreen, CO 80439

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No