USA flag logo/image

An Official Website of the United States Government

Back

Company Information:

Company Name: CRINETICS PHARMACEUTICALS, INC.
City: Leucadia
State: CA
Zip+4: 92024-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $816,248.00 3

Award List:

Biosensors of GPCR Activation and Inhibition for Drug Discovery

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Richard S. Struthers
Award Amount: $237,895.00
Abstract:
DESCRIPTION (provided by applicant): Measurements of the affinity, potency and efficacy of ligands to G protein-coupled receptors (GPCRs) are fundamental to pharmacology and drug discovery. Cellular functional assays measuring the production of GPCR second messengers such as cAMP and inositol… More

Biased Agonism In GPCR Drug Discovery: Application To Somatostatin Agonists

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Richard S. Struthers – 858-450-6464
Award Amount: $282,070.00
Abstract:
DESCRIPTION (provided by applicant): Analogs of the neuropeptide somatostatin are important therapeutics for the treatment of hormone secreting tumors with annual sales in excess of 1.3B. However, currently available peptide depots are only effective in approximately half the patients with growth… More

Nonpeptide Kisspeptin Antagonists for PCOS and HPG axis control

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen F. Betz – 858-450-6464
Award Amount: $296,283.00
Abstract:
DESCRIPTION (provided by applicant): During the past decade, the discovery of kisspeptin peptides and their cognate receptor KISS1R (aka GPR54) has expanded our mechanistic understanding of the hypthothalamic-pituitary-gonadal (HPG) axis. The kisspeptin system has been shown to be an integrator of… More
Back