NOVEL PYROGEN REMOVAL SYSTEM
DECRIPTION (Provided by applicant): Pyrogen-free water (PFW) is required in
many applications. Laboratories use it as solvent for compound preparation,
culture media, and equipment rinse. Hospitals use it for cleaning to prepare
solutions for injections, lV's, and hemodialysis. Pharmaceutical manufacturers
use it to formulate injectable drug preparations. Pyrogens, or fever-inducers,
are derived from metabolic byproducts of bacteria, molds, yeasts, viruses, and
Current technology used to prepare PFW include distillation, reverse osmosis,
and ultrafiltration. Overall these processes are complicated, prone to failure,
and in many cases do not remove sufficient pyrogens and are not ideal for small
scale facilities. In this program, Compact Membrane Systems (CMS) has
identified a simple (push one button) system that is easily integrated into
existing systems for pyrogen removal.
The basis of the CMS technology is a novel oxidizing system that both kills
microorganisms and oxidizes their endotoxins. In Phase I we will develop this
novel oxidizing system and demonstrate superior pyrogen removal compared to
PROPOSED COMMERCIAL APPLICATION:
Water for Injection including Kidney Dialysis water and pharmaceutical water.
Small Business Information at Submission:
COMPACT MEMBRANE SYSTEMS, INC.
325 WATER STREET WILMINGTON, DE 18904
Number of Employees: