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THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A DEVICE TO AID IN THE INVESTIGATION…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4874
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4874
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Conaway Inc
Po Box 785 6611 Liggett Road Dublin, OH 43017
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A DEVICE TO AID IN THE INVESTIGATION OF A NOVEL PROCEDURE FOR LONG-TERM CRYOPRESERVATION OF ORGANS.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A DEVICE TO AID IN THE INVESTIGATION OF A NOVEL PROCEDURE FOR LONG-TERM CRYOPRESERVATION OF ORGANS. THE PRESERVATION PROCEDURE INVOLVES THE USE OF ULTRAHIGH HYDROSTATIC PRESSURE (I.E., ABOUT 6300 ATMOSPHERES) DURING THE FREEZING AND THAWING PROCESSES. INTEGRATION OF THIS APPROACH WITH MODIFIED EXISTING PROTOCOLS FOR CRYPPRESERVATION IS ANTICIPATED. THEAPPARATUS WILL APPLY HYDROSTATIC PRESSURES ON THE ORDER OF 6300 ATMOSPHERES IN INTERVALS AS SHORT AS 0.1 SECOND AS WELLAS INDEFINITELY LONGER PERIODS, AND MAINTAIN SUCH PRESSURES AS LONG AS DESIRED. TEMPERATURES WILL BE CONTROLLED INDEPENDENTLY AND WILL RANGE TO BELOW -150 C. THE CHAMBER WILL ACCOMODATE A SAMPLE OF ABOUT 2 CM DIAMETER AND 8 CM LENGTH. PERFORMANCE EVALUATIONS WILL BE CARRIED OUT TO FULLY CHARACTERIZE THE OPERATING RANGE AND TO ESTABLISH THE NECESSITY FOR ANY MODIFICATIONS OF A FINAL COMMERCIAL MODEL.SEVERAL TISSUE SAMPLES WILL BE PROCESSED USING RELATIVELY SIMPLE PROTOCOLS. THESE SAMPLES WILL BE EXAMINED FOR EVIDENCE OF THE EFFECTIVENESS OF THE ULTRAHIGH PRESSURE TECHNIQUE.

Principal Investigator:

Robert m conaway
PRINCIPAL INVESTIGATOR
6147660200

Business Contact:

Small Business Information at Submission:

Conaway Inc
Po Box 785 6611 Liggett Road Dublin, OH 43017

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No