The majority of personnel injured in OIF/OEF have suffered blast effects from IEDs. Blasts often cause cranio-facial trauma that is difficult to repair. There is a significant need to develop better platform technologies for these injuries and translate them into clinical and commercial use. A… More

DESCRIPTION (provided by applicant): This is a proposal to develop a keratin based resuscitation fluid that greatly improves outcomes for patients following treatment of hemorrhage. Inadequate fluid resuscitation technology has contributed to tens of thous ands of lives lost and billions of dollars… More

A principal approach in regenerative medicine is to stimulate or augment endogenous repair mechanisms that promote functional restoration of damaged or diseased tissues. When loss of significant volumes of multiple functionally integrated tissues occurs,

The majority of personnel injured in OIF/OEF have suffered blast injuries from IEDs. Blasts often cause cranio-facial trauma that is difficult to repair surgically. The current standard of care involves the placement of fixation devices and off label use of growth factor carriers. These… More

DESCRIPTION (provided by applicant): Although numerous advances have been made in the treatment of severe hemorrhage, current blood plasma substitutes do not address new insights in resuscitation medicine. Research in fluid technologies and vascular response following significant pre-hospital… More

Injuries to soft tissues in extremities represent a high percentage of battlefield wounds in recent conflicts. Therapies for restoring function to injured muscle are needed for Wounded Warriors suffering from debilitating and sometimes disfiguring musculoskeletal injuries. Regenerative medicine… More

Skeletal muscle injury is a significant challenge to warfighters due to the severity of the injuries often caused by Improvised Explosive Devices. Currently, there are few viable clinical treatment options for these types of injuries. Keratin hydrogels offer a solution to these challenges as… More

The improvement of body armor, equipment, and decreases in patient transport times have dramatically improved survival of combat injuries. However, data suggests that future conflicts will require more aggressive wound management at the point of injury to deal with more complex wounds particularly… More