USA flag logo/image

An Official Website of the United States Government

Automated, portable, concurrent, WMD detection system

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
71221
Program Year/Program:
2004 / STTR
Agency Tracking Number:
AI059138
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Concurrent Analytical, Inc.
150 Hamakua Dr. PMB 702 Kailua, HI 96734 2825
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: Yes
 
Phase 1
Fiscal Year: 2004
Title: Automated, portable, concurrent, WMD detection system
Agency: HHS
Contract: 1R41AI059138-01A1
Award Amount: $994,832.00
 

Abstract:

DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. As a proving ground for this concept, this Phase I effort has three major objectives. The first objective is to develop the requisite Raman active labels and sample handling protocols for the simultaneous, low-level detection (approximately 100 biolites) of simulants for Bacillus anthracis (anthrax), Clostridium botulinum (botulism), Yersinia pestis (plague), and Variola major (smallpox). The second objective is to devise a facile approach for sample concentration that will realize equilibration time's prior to readout of less than one minute. The third objective is to reduce the size and power requirements of our current NanoRamanTM I instrument to that of a 1980's cell phone. Thereby, the combined system of Extrinsic Raman Labels (ERLTM) along with the NanoRamanTM I instrument could function as a highly sensitive detection and labeling method that can be applied in a high throughput format by reading multiple biomarkers concurrently at a single biochip detector (sensor) address, and could be utilized for many portable applications. The successful completion of these three objectives will provide the framework upon which in Phase II, a detection system could be made that can detect all of the pathogens listed in Categories A, B and C that are amenable to immunoassay-based analysis, concurrently, with detection levels approaching single biolite and response times of a few minutes, in a compact, low power, portable device.

Principal Investigator:

Christian L. Schoen
8082636387
CSCHOEN@CONCANA.COM

Business Contact:


8082636387
Small Business Information at Submission:

CONCURRENT ANALYTICAL, INC.
CONCURRENT ANALYTICAL, INC. BOX 1211, 41-1537 KALANIANAOLE HWY, STE 206 WAIMANALO, HI 96795

EIN/Tax ID: 421538908
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
IOWA STATE UNIVERSITY
2207 PEARSON HALL, RM. 15
AMES, IA 50011
RI Type: Nonprofit college or university