DESCRIPTION (provided by applicant): We propose to develop a novel desk-top FT-ICR mass spectrometer with O-trap FT-ICR cell technology for high throughput, ultra-high performance MS and multy-type (CID, ECD, HECD, and EDD) MS/MS analysis (4 - 10 spectra p er second with R = 100,000 - 25,000 at m/z… More

We propose to build a compact, rugged field-deployable laser photoacoustic spectrometric (LPAS) sensor for continuous, real-time measurements of multiple chemical components, and perform field tests to qualify it for dynamic monitoring of Water Vapor, Carbon Dioxide (12CO2 and 13CO2), Carbon… More

MassTech, Inc. proposes to develop a Lidar Wind Profiler for standoff sensing of concurrent 3-component wind velocities using an eye-safe, rugged, reliable optical device. We propose to use a multi-beam lidar system to obtain aerosol backscatter data from the flowfield and to develop a time-lag… More

DESCRIPTION (provided by applicant): The primary goal of this proposal is to develop a novel fragmentation technique based on interaction of peptide ions with radical beam. We plan to demonstrate that this technique will produce different type of fragment ions compared to those obtained in… More

We propose to build a compact, rugged airborne laser photoacoustic spectrometric (LPAS) sensor based on a tunable mid-IR diode laser for continuous, real-time measurements of water vapor, and perform field tests to qualify it for dynamic airborne in situ monitoring of upper troposphere water… More

This Small Business Innovation Research Phase I project aims at developing laser photoacoustic spectroscopy (LPAS) sensor for continuous, real-time measurements of hazardous air pollutants (HAPs), and other air pollutants such as Carbon monoxide, nitrogen oxides, and sulfur dioxide. The intellectual… More

DESCRIPTION (provided by applicant): The primary objective of this proposal is to develop a novel ion source for the efficient on-line coupling of a wide array of chromatographic techniques with mass spectrometry. The use of liquid chromatography separation is a prerequisite for high-throughput mass… More

The development of a standoff sensor that can measure 3D components of wind velocity in the vicinity of an airport has the potential to improve airport throughput, safety and efficiency. The goal of this research is to develop a Lidar Wind Profiler (LWP) that uses multiple near-parallel lidar beams… More

Formaldehyde (HCHO) is of great interest to atmospheric scientists in NASA and other research institutions. In this SBIR project, we propose to build an airborne or ground based, atmospheric formaldehyde (HCHO) profiler implementing Laser Induced Fluorescence (LIF) techniques. The instrument will… More

Formaldehyde (HCHO) is a key trace species that is of great interest to atmospheric scientists in NASA and other research institutions. In this SBIR project, we proposed to build an airborne atmospheric formaldehyde (HCHO) profiler implementing a Laser Induced Fluorescence (LIF) technique. This… More

Aircraft wake vortices is especially hazardous during the landing and taking-off phases of flight. It is essential to obtain an accurate atmospheric temperature profile in the lower troposphere for a better prediction and understanding of aircraft wake vortex. In this NASA SBIR project, we propose… More

The development of a standoff sensor that can measure 3D components of wind velocity in the downwash of a rotorcraft operating near solid surfaces would enable a better understanding of this complicated flowfield and provide data to validate computational models. The goal of this research is to… More

DESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of electron transfer dissociation (ETD) in tandem mass spectrometry (MS) will have a profound impact on its applications to the entire analytical field of characterization of posttranslational modifications (PTM)… More

DESCRIPTION (provided by applicant): Increasing efficiency of ion detection in Fourier Transform Mass Spectrometry (FTMS) can have a tremendous impact on its applications in proteomics and entire analytical field. At present, the sensitivity of FTMS instruments is limited by electrical noise of… More