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A HAND HELD ULTRASONIC METERED DOSE INHALER

Award Information

Agency:
Department of Health and Human Services 		Branch:
N/A 		Award ID:
55670 		Program Year/Program:
2001 / SBIR
Agency Tracking Number:
2R44HL056538-02A1 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
Continuum Dynamics, Inc.
34 Lexington Avenue Ewing, NJ -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2001
Title: A HAND HELD ULTRASONIC METERED DOSE INHALER
Agency: HHS
Contract: N/A
Award Amount: $385,389.00
 

Abstract:

DESCRIPTION (Verbatim from the Applicant's Abstract): The objective of the proposed effort is to develop a hand-held aerosol inhalation delivery system, based on ultrasonic atomization, to replace or augment current metered dose inhalers for both solutions and suspensions. Ultrasonic atomization produces low velocity, monodispersed droplets, which provide excellent lung deposition. The proposed device can deliver drugs for respiratory disease treatment, as well as systemic application that take advantage of the lung's ability to transfer molecules to the blood stream. Electronic control provides precise dose control meet or exceed FDA regulations. Moreover, the ultrasonic-based system does not require a propellant, which will help manufacturers eliminate chlorofluorocarbon-based system and will simplify formulation of their products. The feasibility of the system was demonstrated in Phase I by building and testing a benchtop unit. The Phase II aims are to optimize the Phase I unit by reducing its size and weight while increasing its efficiency. The optimized prototype's performance will determined with solution and suspension formulations in preparation for Phase III clinical trials. Measurements of drop size distributions, drug delivery dose-to-dose repeatability, and atomization rate as function of system parameters will be used to measure performance. PROPOSED COMMERCIAL APPLICATION: Not Available

Principal Investigator:

Andrew E. Kaufman

Business Contact:


6097349282
BARBARA@CONTINUUM-DYNAMICS.COM
Small Business Information at Submission:

CONTINUUM DYNAMICS, INC.
BOX 3073 JAMES FORRESTAL CAMPUS, BLDG 9A PRINCETON, NJ 08543

EIN/Tax ID: 222248930
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No