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An Enhanced Medication Monitoring Program

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
96307
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
HL097395
Solicitation Year:
N/A
Solicitation Topic Code:
NHLBI
Solicitation Number:
N/A
Small Business Information
MEDMINDER SYSTEMS, INC.
73 HAMLET ST. NEWTON, MA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: An Enhanced Medication Monitoring Program
Agency: HHS
Contract: 1R43HL097395-01A1
Award Amount: $427,628.00
 

Abstract:

DESCRIPTION (provided by applicant): The goal of the Enhanced Medication Management Program (eMMp) being developed by MedMinder Systems, Inc. is to increase the ability of frail elders to adhere to complex medication regimens for chronic conditions. Ad herence will facilitate effective self-care and decrease personal and societal costs associated with disease progression and loss of independence. Multiple studies have shown that more frequent personal follow-up is the most effective way to maximize medic ation adherence, but such personal care is too costly to translate well to real life in a world of limited healthcare resources. Currently available smart pillboxes are too expensive, too limited in the number and types of medica- tions delivered, and t oo technically complex for the large majority of senior citizens. The eMMp is designed to deliver prompts and reminders to the user, to be remotely programmable by caregivers, to allow the option of using pre-filled medication trays, to provide electronic adherence reports to family/caregivers and to provide personalized reinforcing phone calls from professional caregivers, all at a modest cost. The in-home ReMinder will use a familiar pillbox layout (4 doses/day for 7 days) and allow easy removal of medica tion cups by elderly, rheumatic fingers. Installation will require only an electrical outlet (no modems or dedicated phone lines). Once plugged in, the built-in pager will continuously download remotely programmed visual and/or aural prompts and reminders from a central server (RemoteMind). It will continuously upload the date and time when each medi- cation cup is removed and when weekly refill is carried out, enabling remote adherence monitoring, alerts to caregivers, and follow-up intervention(s) from pe rsonal and/or professional caregivers as needed. The hypothesis to be tested in this 2 year SBIR Phase I work plan is that the eMMp will significantly im- prove adherence and clinical outcome (blood pressure control) in a population of frail elderly who a re hyper- tensive. Specific aims are: 1) to finalize upgrades to the existing RemoteMind web server and to manufacture and release test 175 ReMinder units, and 2) to conduct a randomized clinical trial (150 hypertensive, elderly volunteers; 3-month run-in period, 6-month intervention period) to test whether the fully activated eMMp (pro- viding in-home prompts and reminders, automated reminder calls, and reinforcing personal calls from a profes- sional caregiver as required) can increase medication adherenc e by at least 25% and reduce systolic blood pressure by at least 8 mm Hg during the intervention period. Assuming a 10% dropout rate during each phase (run-in and intervention), the trial is expected have 80% power to detect improved medication adherence a nd 95% power to detect reduced systolic blood pressure. Effects of the intervention on attitudes toward medica- tion, perceived ability to self manage complex medication regimens and unscheduled use of healthcare ser- vices will also be assessed. SBIR Phas e II will determine the minimum level of intervention needed to achieve sustained medication adherence and control of blood pressure in a larger group of hypertensive elders. PUBLIC HEALTH RELEVANCE: Project Narrative Although 125 million Ameri cans suffer from at least one chronic condition (high blood pressure, heart failure, diabetes, etc.) and 65% of individuals over 65 suffer from two or more such conditions, an estimated 30-60% of them fail to take their medications at the times and/or dose s prescribed. Such medication non-adherence undermines attempts to prevent disease progression, is responsible for an estimated 23% of nursing home admissions, and increases healthcare costs by as much as 100 billion annually. MedMinder's goal is to deter mine whether its Enhanced Medication Management Program (eMMp) can significantly improve me- dication adherence, resulting in better blood pressure control in a group of frail elderly by enabl- ing cost-effective personalized reinforcement from caregivers.

Principal Investigator:

Andrew Dibner

Business Contact:

Eran Shavelsky
eran@medminder.com
Small Business Information at Submission:

MEDMINDER SYSTEMS, INC.
73 HAMLET ST. NEWTON, MA -

EIN/Tax ID: 126044967
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No