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Seachange Pharmaceuticals, Inc.
http://www.seachangepharma.com
UEI: N/A
# of Employees: 2
HUBZone Owned: No
Socially and Economically Disadvantaged: No
Woman Owned: No
Award Charts
Award Listing
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Relating GPCRs by biased ligands for enhanced therapeutic efficacy
Amount: $301,225.00DESCRIPTION (provided by applicant): Goals: The goal is to expand the known pharmacological relationships among arrestin and G protein biased ligands. Starting with the Gi-coupled dopamine D2 rec ...
SBIRPhase I2013Department of Health and Human Services National Institutes of Health -
A platform to predict side-effect targets for drugs
Amount: $909,637.00DESCRIPTION (provided by applicant): Bioactive small molecules can act on multiple targets, and these off-target activities underlie many of the adverse reactions from which drugs suffer. The motivati ...
SBIRPhase II2013Department of Health and Human Services National Institutes of Health -
Calculating target bias in small molecules for library design
Amount: $250,241.00DESCRIPTION (provided by applicant): Goals: The goal is to develop a computational system to predict the targets toward which small molecules are biased. The tool will optimize biased libraries, prior ...
SBIRPhase I2011Department of Health and Human Services National Institutes of Health -
Drug Repurposing using Pharmacological Networks
Amount: $202,500.00DESCRIPTION (provided by applicant): Three ideas motivate this project. First, bioactive small molecules often act on multiple targets- sometimes this polypharmacology is key to their efficacy, some ...
SBIRPhase I2010Department of Health and Human Services National Institutes of Health
