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Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
96546
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
N43CO201000136
Solicitation Year:
N/A
Solicitation Topic Code:
NCI
Solicitation Number:
N/A
Small Business Information
ORANOXIS, INC.
10366 ROSELLE ST SAN DIEGO, CA 92121-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: Not Available
Agency: HHS
Contract: N43CO201000136
Award Amount: $200,000.00
 

Abstract:

Different patients react very differently to chemotherapeutic cancer drugs, and are variably susceptible to drug side effects. Many patients are therefore currently not receiving adequate levels of those drugs. A personalized monitoring of toxic drug metabolites would greatly aid physicians to accurately personalize drug dosage.    We propose to develop a rapid oral fluid test of a panel of small drug metabolites for personalized diagnostic monitoring during treatment. We will utilize our patented design for a "discontinuous chromatographic capillary flow solid phase assay", The test can be designed both for home self-monitoring by the patient (over-the-counter device) and for use by physicians in clinics (point-of-care). The key features include: (i), highly sensitive detection of small molecule drug metabolites; (ii), an integrated oral fluid collection design that minimizes sample variability in viscosity, pH and contents, and provides sufficient sample backupvolumes for subsequent confirmatory tests; (iii), a user-friendly, low cost and disposable device.

Principal Investigator:

Daniel Wang
Small Business Information at Submission:

ORANOXIS, INC.
10366 ROSELLE ST SAN DIEGO, CA 92121-

EIN/Tax ID: 264656721
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No